Evidence map›Paper›PMID 42168426›Full record

ArticleScientific reports2026

Postbiotic derived from Lacticaseibacillus paracasei CNCM I-5220 as a novel approach to improve ageing-induced skin damage.

Francesca Algieri, Silvia Pimazzoni, Nina Tanaskovic, Daniele Braga, Giuseppe Penna, Maria Rescigno

Abstract read
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In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Francesca Algieri *Postbiotica S.r.l., Milan, Italy.
Silvia Pimazzoni *Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Italy.
Nina TanaskovicPostbiotica S.r.l., Milan, Italy.
Daniele BragaIRCCS Humanitas Research Hospital, Rozzano, Italy.
Giuseppe PennaPostbiotica S.r.l., Milan, Italy.
Maria RescignoDepartment of Biomedical Sciences, Humanitas University, Pieve Emanuele, Italy. maria.rescigno@hunimed.eu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ageing process impacts skin health by reducing cell turnover and altering skin microbiota, which plays a crucial role in maintaining homeostasis and protection against pathogens. Microbiota-derived metabolites, including postbiotics generated through nutrient fermentation, may contribute to these protective functions. In this context, topical application of postbiotics represents a promising strategy to mitigate visible signs of skin ageing. We investigated the effects of PB-SKF, a postbiotic derived from the fermentation of fructooligosaccharides (FOS) by Lacticaseibacillus paracasei strain CNCM I-5220

Indexed as

Lacticaseibacillus paracaseiSkinSkin AgingCell MovementCollagenFibroblastsHumansHyaluronic AcidKeratinocytesSkin MicrobiomeWound HealingCollagenHyaluronic AcidCollagenHyaluronic acidLacticaseibacillus paracaseiPostbioticSkin ageing

Identifiers

PMID42168426
PMCPMC13503780

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.