Evidence map›Paper›PMID 42168325›Full record

ArticleScientific reports2026

Introgression of QTL hotspot regions enhances grain yield and maize lethal necrosis resistance in elite maize lines.

Veronica Ogugo, Vijay Chaikam, Michael S Olsen, Yoseph Beyene, L M Suresh, Liezel Herselman, MacDonald Bright Jumbo, Prasanna M Boddupalli, Manje Gowda

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In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Veronica OgugoInternational Maize and Wheat Improvement Center (CIMMYT), World Agroforestry Centre (ICRAF), United Nations Avenue, Gigiri, P.O. Box 1041-00621, Nairobi, Kenya.
Vijay ChaikamInternational Maize and Wheat Improvement Center (CIMMYT), World Agroforestry Centre (ICRAF), United Nations Avenue, Gigiri, P.O. Box 1041-00621, Nairobi, Kenya.
Michael S OlsenInternational Maize and Wheat Improvement Center (CIMMYT), World Agroforestry Centre (ICRAF), United Nations Avenue, Gigiri, P.O. Box 1041-00621, Nairobi, Kenya.
Yoseph BeyeneInternational Maize and Wheat Improvement Center (CIMMYT), World Agroforestry Centre (ICRAF), United Nations Avenue, Gigiri, P.O. Box 1041-00621, Nairobi, Kenya.
L M SureshInternational Maize and Wheat Improvement Center (CIMMYT), World Agroforestry Centre (ICRAF), United Nations Avenue, Gigiri, P.O. Box 1041-00621, Nairobi, Kenya.
Liezel HerselmanDepartment of Plant Sciences, University of the Free State, P.O. Box 339, Bloemfontein, 9300, South Africa.
MacDonald Bright JumboInternational Maize and Wheat Improvement Center (CIMMYT), World Agroforestry Centre (ICRAF), United Nations Avenue, Gigiri, P.O. Box 1041-00621, Nairobi, Kenya.
Prasanna M BoddupalliInternational Maize and Wheat Improvement Center (CIMMYT), World Agroforestry Centre (ICRAF), United Nations Avenue, Gigiri, P.O. Box 1041-00621, Nairobi, Kenya.
Manje GowdaInternational Maize and Wheat Improvement Center (CIMMYT), World Agroforestry Centre (ICRAF), United Nations Avenue, Gigiri, P.O. Box 1041-00621, Nairobi, Kenya. m.gowda@cgiar.org.

Funding

Bill & Melinda Gates Foundation INV-003439Gates Foundation INV-003439
6 · The paper itself

Abstract

Maize lethal necrosis (MLN) poses a severe threat to maize production in eastern and southern Africa, causing significant yield losses. In this study, marker-assisted backcross introgression (MABI) was used to introgress major-effect MLN resistance Quantitative Trait Loci (QTL). These QTLs located on chromosomes 3 and 6, were introgressed into 14 MLN-susceptible CIMMYT maize lines. Ten Kompetitive Alelle Specific PCR (KASP) SNP markers closely linked to three validated QTL-hotspot regions were applied for foreground selection, with at least two hotspots polymorphic across all donor-recipient combinations. Foreground and background selection enabled fast tracking of MLN resistance alleles and recovery of near-recurrent parent genomes. The resulting BC₄F

Indexed as

Disease ResistanceGenetic IntrogressionPlant DiseasesQuantitative Trait LociZea maysChromosome MappingChromosomes, PlantEdible GrainPhenotypePolymorphism, Single NucleotideDisease severityGrain yieldMABIMaizeMLN resistanceQTL

Identifiers

PMID42168325
PMCPMC13396450

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.