Evidence map›Paper›PMID 42168199›Full record

ArticleNPJ Parkinson's disease2026

Exploring fNIRS-guided neurofeedback for supplementary motor area training in Parkinson's disease and healthy older adults.

Franziska Klein, Michael Lührs, Stefanie Topp, Stefan Debener, Karsten Witt, Cornelia Kranczioch

Abstract read
In one paragraph

Article in NPJ Parkinson's disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Franziska KleinBiomedical Devices and Systems Group, R&D Division Health, OFFIS-Institute of Information Technology, Oldenburg, Germany. franziska.klein@uol.de.
Michael LührsFaculty of Psychology and Neuroscience, Maastricht University, Maastricht, The Netherlands.
Stefanie ToppNeurocognition and Functional Neurorehabilitation Group, Department of Psychology, University of Oldenburg, Oldenburg, Germany.
Stefan DebenerNeuropsychology Lab, Department of Psychology, University of Oldenburg, Oldenburg, Germany.
Karsten WittResearch Center Neurosensory Science, University of Oldenburg, Oldenburg, Germany.
Cornelia KrancziochNeurocognition and Functional Neurorehabilitation Group, Department of Psychology, University of Oldenburg, Oldenburg, Germany. cornelia.kranczioch@uol.de.

Funding

Bundesministerium für Bildung und Forschung 01IS22085ESchool of Medicine and Healthcare Sciences, University of Oldenburg (2017-2020)
6 · The paper itself

Abstract

Parkinson's disease (PD) is typically treated with medication, which often leads to side effects. This study investigated a non-pharmacological approach combining motor imagery (MI) with neurofeedback (NFB) guided by functional near-infrared spectroscopy (fNIRS) to enhance supplementary motor area (SMA) activation during MI. Three groups (N = 18 each) completed four sessions: a PD-NFB group, a healthy NFB group, and a healthy control group without NFB. The NFB groups received feedback based on decreased Δ[HbR], reflecting increased brain activity. The control group performed MI without feedback. Participants in the NFB groups generally perceived NFB to be manageable. The healthy NFB group showed significantly higher SMA activation than the noNFB group. No significant differences were observed between the PD and healthy NFB groups, or between baseline and NFB-MI in PD. This first fNIRS-guided MI-NFB study in PD (German Clinical Trials Register, DRKS-ID: DRKS00022997, DOR: 2020-10-02). Shows promise for motor rehabilitation, but also highlights further research and protocol refinement.

Identifiers

PMID42168199
PMCPMC13310843

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.