Evidence map›Paper›PMID 42166546›Full record

ArticleVirulence2026

Grass carp catalase inhibits GCRV replication through ROS scavenging-mediated immune suppression and autophagy.

Xuyang Wang, Xiaowen Zou, Linlin Liu, Xinyu Liang, Hanyue Wang, Cheng Yang, Yongming Li, Lanjie Liao, Zuoyan Zhu, Yaping Wang and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Virulence, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Xuyang WangState Key Laboratory of Breeding Biotechnology and Sustainable Aquaculture, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
Xiaowen ZouState Key Laboratory of Breeding Biotechnology and Sustainable Aquaculture, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
Linlin LiuInstitute of Medical Equipment Science and Engineering, Huazhong University of Science and Technology, Wuhan, China.
Xinyu LiangState Key Laboratory of Breeding Biotechnology and Sustainable Aquaculture, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
Hanyue WangState Key Laboratory of Breeding Biotechnology and Sustainable Aquaculture, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
Cheng YangState Key Laboratory of Breeding Biotechnology and Sustainable Aquaculture, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
Yongming LiState Key Laboratory of Breeding Biotechnology and Sustainable Aquaculture, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
Lanjie LiaoState Key Laboratory of Breeding Biotechnology and Sustainable Aquaculture, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
Zuoyan ZhuState Key Laboratory of Breeding Biotechnology and Sustainable Aquaculture, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
Yaping WangState Key Laboratory of Breeding Biotechnology and Sustainable Aquaculture, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
Jingjing ZhaoInstitute of Medical Equipment Science and Engineering, Huazhong University of Science and Technology, Wuhan, China.ORCID 0000-0003-0937-2751
Libo HeState Key Laboratory of Breeding Biotechnology and Sustainable Aquaculture, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.ORCID 0000-0002-7058-5791

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Catalase (CAT) is a key antioxidant enzyme that eliminates reactive oxygen species (ROS), thereby protecting organisms from oxidative stress and maintaining cellular homeostasis. In this study, we cloned and characterized a CAT gene (CiCAT) from grass carp (

Indexed as

AutophagyCarpsCatalaseFish DiseasesReactive Oxygen SpeciesReoviridaeVirus ReplicationAmino Acid SequenceAnimalsCloning, MolecularEscherichia coliFish ProteinsHydrogen PeroxidePhylogenyReoviridae InfectionsCatalaseFish ProteinsHydrogen PeroxideReactive Oxygen SpeciesautophagycatalaseGrass carpgrass carp reovirusimmune responseinterferons

Identifiers

PMID42166546
PMCPMC13240956

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.