Evidence map›Paper›PMID 42166483›Full record

ArticlePloS one2026

Evaluation of the effect of refined management of prospective prescription review rules for antimicrobial agents in an outpatient setting of a county-level hospital in China.

Dong Pan, Zhewen Lu, Ye Yan

Abstract read
In one paragraph

Article in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Dong PanDepartment of Pharmacy, Yangming Hospital Affiliated to Ningbo University (Yuyao People's Hospital), Yuyao, Zhejiang, China.
Zhewen LuDepartment of Pharmacy, Yangming Hospital Affiliated to Ningbo University (Yuyao People's Hospital), Yuyao, Zhejiang, China.
Ye YanDepartment of Pharmacy, Yangming Hospital Affiliated to Ningbo University (Yuyao People's Hospital), Yuyao, Zhejiang, China.ORCID https://orcid.org/0009-0000-7601-6218

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo explore the impact of implementing a refined management system for prospective prescription review and to provide evidence for improving the rational use of antibiotics in county-level hospitals.

methodsUsing the prospective prescription review system at Affiliated Yangming Hospital of Ningbo University, China, we performed a refined management of the review rules targeting major issues identified in outpatient antibiotic prescriptions. A comparative analysis was conducted to evaluate the rationality of prescriptions before and after the implementation of this refined management.

resultsComparison of prescription data before and after the refined management showed that the rate of irrational outpatient antibiotic prescriptions decreased from 20.46% to 7.80%. Specifically, the proportion of prescriptions with inappropriate indications decreased from 2.65% to 0.67%. The rate of prescriptions with an inappropriate frequency of administration or unsuitable solvent decreased from 4.63% to 0.79%. Prescriptions with an inappropriate dosage or route decreased from 8.14% to 2.09%. Irrational prescriptions for special populations decreased from 1.36% to 1.21%, and those involving potential drug-drug interactions decreased from 3.68% to 3.03%.

conclusionThe refined management of prospective antibiotic prescription review rules in the outpatient department of this county-level hospital significantly reduced the rate of irrational prescriptions. This strategy is worthy of promotion and application in other similar hospitals.

Indexed as

Anti-Bacterial AgentsAnti-Infective AgentsDrug PrescriptionsDrug Utilization ReviewHospitals, CountyChinaHumansInappropriate PrescribingOutpatientsProspective StudiesAnti-Bacterial AgentsAnti-Infective Agents

Identifiers

PMID42166483
PMCPMC13193398

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.