ArticleNeuro-degenerative diseases2026
Cognitive Impairment Is Associated with Disrupted Motor Planning in Older Adults.
Article in Neuro-degenerative diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
<p>Introduction: Neurocognitive disorders (NCD) are frequently accompanied by motor impairments that may precede overt cognitive decline. However, most motor markers remain coarse and do not disentangle global motor deterioration from disruptions of specific motor control processes. Motor planning, a process relying on both motor and cognitive resources, may be particularly vulnerable to cognitive impairment yet has rarely been investigated using process-specific motor control frameworks.
methodsWe assessed motor planning abilities in 57 older adults, including cognitively impaired (CI; n = 27) and healthy adult (HA; n = 30) participants. Using a gravity-related motor planning paradigm, participants performed vertical arm movements requiring different interactions with gravitational torque. Directional asymmetries in movement kinematics were used as a process-specific proxy of motor planning. Movement smoothness was quantified using jerk-based measures as a complementary index of global motor execution. Movement duration was carefully controlled across groups and directions, and age effects were accounted for in the analyses.
resultsMovement duration did not differ between groups. Compared with HA participants, the CI group exhibited reduced directional asymmetries, indicating altered motor planning. Within the CI group, the magnitude of directional asymmetries was positively correlated with cognitive status, as assessed by the Mini-Mental State Examination. In contrast, although movement smoothness was globally reduced in CI participants, jerk-based measures were not associated with cognitive status after controlling for age and movement duration.
conclusionThese findings suggest that cognitive impairment in older adults is specifically associated with a disruption of motor planning processes rather than a uniform degradation of motor execution. By dissociating global motor deterioration from planning-related decompensation, this study highlights the value of process-specific motor control measures for understanding sensorimotor alterations in NCD and their potential relevance for early detection. </p>.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.