ReviewFEMS microbiology reviews2026
The role of fungal G protein-coupled receptors in interspecies cell-cell communication.
Review in FEMS microbiology reviews, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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3 authors.
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Abstract
Fungi occupy a wide range of ecological niches in which they compete or associate with other organisms through the perception of external signals and appropriate cellular responses. Fungal G protein-coupled receptors (GPCRs) are seven-transmembrane domain proteins that mediate the perception of extracellular cues. Despite their critical importance, the majority of fungal GPCRs are currently orphan receptors with unknown ligands and functions. In this review, we summarize the current knowledge on the role of fungal GPCRs in the perception of non-self signals and address persistent inconsistencies in the literature regarding fungal GPCR classification. We propose a refined system that differentiates between characterized, proposed, and uncharacterized GPCRs. Finally, we discuss how synthetic biology tools and experimental work in the native fungal organisms can elucidate the physiological role of fungal GPCRs during interspecies cell-cell communication.
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