Evidence map›Paper›PMID 42166096›Full record

ArticleUpdates in surgery2026

Laparoscopic versus robotic surgery in the setting of combined resection of colorectal cancer and liver metastases: an experience from the I Go MILS registry.

Giorgio Traina, Rebecca Marino, Alessandro Ferrero, Felice Giuliante, Andrea Ruzzenente, Giorgio Ercolani, Umberto Cillo, Vincenzo Mazzaferro, Giuseppe Maria Ettorre, Andrea Belli and 4 more

Abstract readComparative StudyMulticenter Study
PubMed Publisher
In one paragraph

Article in Updates in surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Giorgio TrainaHepatobiliary Surgery Division, IRCCS San Raffaele Scientific Institute, 20134, Milan, Italy.
Rebecca MarinoHepatobiliary Surgery Division, IRCCS San Raffaele Scientific Institute, 20134, Milan, Italy.
Alessandro FerreroDepartment of Surgery, Mauriziano Hospital, 10128, Turin, Italy.
Felice GiulianteHepatobiliary Surgery Unit, Fondazione Policlinico Universitario A. Gemelli IRCSS, Università Cattolica del Sacro Cuore, 00136, Rome, Italy.
Andrea RuzzenenteDivision of General and Hepatobiliary Surgery, G.B, Rossi University Hospital, University of Verona, 37134, Verona, Italy.
Giorgio ErcolaniGeneral and Oncology Surgery, Morgagni-Pierantoni Hospital, Ausl Romagna, 47121, Forlì, Italy.
Umberto CilloHepato-Biliary-Pancreatic Surgery and Liver Transplant Unit, General Surgery 2, Department of Surgical, Oncological and Gastroenterological Sciences, University of Padua, 35128, Padua, Italy.
Vincenzo MazzaferroDivision of HPB Surgery and Liver Transplantation, Department of Surgery, Fondazione IRCCS Istituto Nazionale Tumori Di Milano, 20133, Milan, Italy.
Giuseppe Maria EttorreDepartment of Surgery, San Camillo Forlanini Hospital, 00152, Rome, Italy.
Andrea BelliHepatobiliary Unit, Division of Surgical Oncology, Istituto Nazionale Tumori IRCCS Fondazione "G. Pascale", 80131, Naples, Italy.
Elio JovineDepartment of Medical and Surgical Sciences, Alma Mater Studiorum, University of Bologna, 40138, Bologna, Italy.
Pierpaolo SileriColorectal Surgery Division, IRCCS San Raffaele Scientific Institute, 20134, Milan, Italy.
Francesca RattiHepatobiliary Surgery Division, IRCCS San Raffaele Scientific Institute, 20134, Milan, Italy. ratti.francesca@hsr.it.ORCID http://orcid.org/0000-0002-8108-9064
I Go MILS Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Approximately 25% of patients with colorectal cancer (CRC) are diagnosed with distant metastases, with the liver being the most common site. A simultaneous approach to resections in these patients may lead to higher complication rates. Recent research suggests that minimally invasive surgical (MIS) techniques can help reduce this additional morbidity. This study examines a multicenter Italian experience, comparing perioperative outcomes of robotic (RS) and laparoscopic surgery (LS) in this setting. Patients from the prospective multicentre registry of the Italian Group of Minimally Invasive Liver Surgery (I Go MILS) who underwent MIS simultaneous resection for CRC with colorectal liver metastasis between 2015 and 2025 were included. Perioperative outcomes were compared between RS and LS using nearest neighbor matching with 2:1 ratio and caliper of 0.2 to mitigate the selection bias. A total of 505 patients were analyzed, including 415 undergoing LS and 90 undergoing RS. After matching, demographic characteristics were similar. Operative time, conversion rate (11.71% for LS vs 6.67% for RS, p = 0.224) and length of stay were comparable between the two groups. Robotic surgery enabled more challenging resections compared to laparoscopy and after matching for complexity was associated with lower major complications (21.62% vs 8.89%, p = 0.014). The robotic approach has demonstrated superior feasibility for technically challenging resections while maintaining similar length of stay, rate of conversion and postoperative complications, after matching for complexity RS was associated with a significantly lower rate of major complications. Robotic surgery can be an alternative to open surgery in complex cases in order to maximise the benefits of minimally invasive surgery and to have better short term postoperative outcomes.

Indexed as

Colorectal NeoplasmsHepatectomyLaparoscopyLiver NeoplasmsRegistriesRobotic Surgical ProceduresAgedFemaleHumansItalyLength of StayMaleMiddle AgedMinimally Invasive Surgical ProceduresOperative TimePostoperative ComplicationsColorectal liver metastasesLaparoscopicMinimally invasiveRoboticSynchronous

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.