Evidence map›Paper›PMID 42166070›Full record

SynthesisCurrent osteoporosis reports2026

Cone Beam Computed Tomography of Bonejaws in Patients With Primary Osteoporosis: A Systematic Review.

Irene Frassineti, Lorenzo Cinci, Andrea Magnini, Maria Pisano, Luigi Barbato, Francesco Cairo, Luisella Cianferotti, Cosimo Nardi

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Current osteoporosis reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Irene FrassinetiDepartment of Experimental and Clinical Medicine, Research Unit in Periodontology and Periodontal Medicine, University of Florence, Florence, Italy.
Lorenzo CinciDepartment of Experimental and Clinical Biomedical Sciences, Radiology Emergency Unit, University of Florence, Florence, Italy.ORCID http://orcid.org/0000-0002-1799-4828
Andrea MagniniDepartment of Experimental and Clinical Biomedical Sciences, Radiology Emergency Unit, University of Florence, Florence, Italy.ORCID http://orcid.org/0009-0005-5132-5053
Maria PisanoDepartment of Experimental and Clinical Biomedical Sciences, Radiology Emergency Unit, University of Florence, Florence, Italy.ORCID http://orcid.org/0009-0003-0872-2147
Luigi BarbatoDepartment of Experimental and Clinical Medicine, Research Unit in Periodontology and Periodontal Medicine, University of Florence, Florence, Italy.ORCID http://orcid.org/0000-0002-0524-7980
Francesco CairoDepartment of Experimental and Clinical Medicine, Research Unit in Periodontology and Periodontal Medicine, University of Florence, Florence, Italy.ORCID http://orcid.org/0000-0003-3781-1715
Luisella CianferottiDepartment of Experimental and Clinical Biomedical Sciences, Bone Metabolic Diseases Unit, University of Florence, Florence, Italy.ORCID http://orcid.org/0000-0001-7424-6212
Cosimo NardiDepartment of Experimental and Clinical Biomedical Sciences, Radiology Emergency Unit, University of Florence, Florence, Italy. cosimo.nardi@unifi.it.ORCID http://orcid.org/0000-0002-5489-7824

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewThis study aimed to investigate the potential of Cone Beam Computed Tomography (CBCT) parameters to identify primary osteoporosis in jawbones. RECENT

findingsEarly diagnosis of osteoporosis is crucial but challenging. Dual X-ray Absorptiometry (DXA) is the gold standard to measure bone density, nevertheless it has limitations including cost, radiation dose, and 2D imaging. CBCT is a volumetric imaging technique commonly used in dentistry that showed promise as an alternative tool due to its high spatial resolution and excellent analysis of bone structures. Mandibular and maxillary CBCT indices showed a strong correlation with Bone Mineral Density (BMD) assessed by DXA. Regional indices (Anterior, Molar, and Posterior), quantitative indices (Computed Tomography Mandibular Index, Computed Tomography Index Superior and Inferior), Radiographic Density, Fractal Dimension, and the qualitative index named Computed Tomography Cortical Index seemed appropriate for the detection of primary osteoporosis. Morphometric parameters for trabecular bone did not show differences between osteoporotic and non-osteoporotic patients. Future studies should assess diagnostic accuracy of such CBCT indices and formulate standardized measurement protocols.

Indexed as

Cone-Beam Computed TomographyMandibleMaxillaOsteoporosisAbsorptiometry, PhotonBone DensityCancellous BoneHumansBone Mineral DensityCone Beam Computed TomographyDual X-ray AbsorptiometryJawsMaxillofacialOsteoporosis

Identifiers

PMID42166070
PMCPMC13194293

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.