Evidence map›Paper›PMID 42166043›Full record

ArticleJournal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie2026

Association between dietary active microbe intake and dental caries among American adults : Evidence from the NHANES database.

Bo Zhang, Lin Lang, Ying Li, Peipei Wang, Ziting Zhao, Wulong Du, Weijia Ye, Jiayong Zhong

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Article in Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Bo ZhangLishui Central Hospital, The Fifth Affiliated Hospital of Wenzhou Medical University, Lishui Hospital of Zhejiang University, Lishui, China.
Lin LangLishui Central Hospital, The Fifth Affiliated Hospital of Wenzhou Medical University, Lishui Hospital of Zhejiang University, Lishui, China.
Ying LiLishui Central Hospital, The Fifth Affiliated Hospital of Wenzhou Medical University, Lishui Hospital of Zhejiang University, Lishui, China.
Peipei WangLishui Central Hospital, The Fifth Affiliated Hospital of Wenzhou Medical University, Lishui Hospital of Zhejiang University, Lishui, China.
Ziting ZhaoLishui Central Hospital, The Fifth Affiliated Hospital of Wenzhou Medical University, Lishui Hospital of Zhejiang University, Lishui, China.
Wulong DuLishui Central Hospital, The Fifth Affiliated Hospital of Wenzhou Medical University, Lishui Hospital of Zhejiang University, Lishui, China.
Weijia YeLishui Central Hospital, The Fifth Affiliated Hospital of Wenzhou Medical University, Lishui Hospital of Zhejiang University, Lishui, China.
Jiayong ZhongThe Affiliated Hospital of Jiaxing University & The First Hospital of Jiaxing, Jiaxing, China. Jiayongg_ZH@outlook.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveDental caries (DC), a biofilm-mediated permanent disease, affects approximately 50% of the global population. Diet is an important modifiable factor among many factors affecting DC. At present, the health benefits of foodborne microbe intake are widely recognized. We aimed to study the association of dietary active microbe intake with the occurrence of DC among American adults. MATERIALS AND

methodsData of adults with complete clinical information were extracted from the National Health and Nutrition Examination Surveys (NHANES) 2015-2020. Occurrence of untreated DC was the primary outcome and DC experience was the secondary outcome. Dietary active microbe intake was divided into three groups: G1 (low), G2 (medium), and G3 (high). Logistics models were performed to test the association of dietary DC with untreated DC and DC experience. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated. Further subgroup analyses were performed to verify whether the association between them remained robust.

resultsA total of 12,762 subjects were included; among them, 3458 (27.10%) had untreated DC. After adjusting all covariates, we observed subjects with G2 and G3 levels of dietary active microbe intake had lower occurrence of untreated DC (G2, OR = 0.81, 95%CI 0.69-0.94; G3, OR = 0.72, 95%CI 0.61-0.84). Subjects with G3 level of dietary active microbe intake were linked to a lower incidence of DC experience (OR = 0.72, 95%CI 0.55-0.94). Subgroup analysis suggested a robust association of dietary active microbe intake and untreated DC and DC experience.

conclusionOur study suggested the potential advantage of high levels of dietary active microbe intake for the prevention of DC in American adults.

Indexed as

Caries preventionDental caries experienceNational Health and Nutrition Examination Surveys databaseOral microbiotaUntreated dental caries

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.