ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2026
Association between dietary inflammatory index and Bell's palsy: a retrospective case-control study.
Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectivesBell's palsy (BP) is an acute facial nerve disorder characterized by rapid-onset unilateral paralysis, in which inflammatory and immune-mediated processes are implicated. The Dietary Inflammatory Index (DII) quantifies the inflammatory potential of the diet and reflects systemic inflammatory burden. However, its association with BP has not been previously investigated.
methodsThis retrospective case-control study included 30 patients with newly diagnosed BP and 30 age- and sex-matched controls without a history of facial paralysis. Dietary intake was assessed using a validated food frequency questionnaire, and DII scores were calculated using standardized methodology. Group differences were analyzed using appropriate statistical tests. Multivariable logistic regression evaluated the association between DII and BP after adjustment for age, sex, and body mass index. Receiver operating characteristic (ROC) analysis assessed discriminatory performance.
resultsPatients with BP had significantly higher DII scores than controls (2.54 ± 1.86 vs. 1.18 ± 1.33; p = 0.002). The BP group also exhibited higher intakes carbohydrates, total fat, saturated fat, monounsaturated fat, and sodium (all p < 0.01). Each 1-unit increase in DII score was independently associated with BP (adjusted OR = 1.70; 95% CI: 1.18-2.47; p = 0.005). ROC analysis demonstrated moderate discriminatory ability (AUC = 0.753; 95% CI: 0.626-0.879).
conclusionHigher dietary inflammatory potential is associated with Bell's palsy, indicating a more pro-inflammatory dietary profile; however, causality cannot be inferred.
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