Evidence map›Paper›PMID 42165773›Full record

ArticleJACC. Case reports2026

Organizing Hematoma Involving a Native Tricuspid Valve: Fatal Case of Cardiac Behçet Disease-Hughes-Stovin Syndrome Overlap.

Zaid Naseer, Venu Peddibhotla, Sebhat Erqou, Aaron Schatz, Anna Tomdio, Daniel Ruiz

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Zaid NaseerDepartment of Internal Medicine, Mary Washington Healthcare, Fredericksburg, Virginia, USA. Electronic address: zaid.naseer@mwhc.com.
Venu PeddibhotlaDepartment of Internal Medicine, Mary Washington Healthcare, Fredericksburg, Virginia, USA.
Sebhat ErqouMary Washington Cardiology, Mary Washington Healthcare, Fredericksburg, Virginia, USA.
Aaron SchatzMary Washington Cardiology, Mary Washington Healthcare, Fredericksburg, Virginia, USA.
Anna TomdioMary Washington Cardiology, Mary Washington Healthcare, Fredericksburg, Virginia, USA.
Daniel RuizCardiology Associates of Fredericksburg, Fredericksburg, Virginia, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBehçet disease (BD) is a multisystem vasculitis with variable cardiovascular involvement. Hughes-Stovin syndrome (HSS), featuring pulmonary artery aneurysms and venous thrombosis, is considered a rare variant within the BD spectrum. Intracardiac mass formation in either vasculitis is exceptionally rare. CASE SUMMARY: A 32-year-old man with prior mucocutaneous ulcers presented with hemoptysis and chest pain. Multimodality imaging revealed pulmonary arterial thrombosis and lobulated intracardiac mass attached to the native tricuspid valve (TV). Histopathology showed inflammatory organizing hematoma. Despite anticoagulation and valve replacement, the patient developed pulmonary artery pseudoaneurysms and died from fatal hemorrhage. DISCUSSION: Eight similar cases in the literature revealed a pattern of TV masses, pulmonary artery aneurysms, and hemoptysis in young male patients, suggesting a cardiac-predominant BD-HSS overlap syndrome. TAKE-HOME MESSAGES: An under-recognized syndrome shares overlapping features of BD and HSS, a common denominator being unusual TV masses. In patients with pulmonary artery involvement, immunosuppressive therapy is critical, and anticoagulation requires caution given aneurysmal rupture risk.

Indexed as

Behçet diseaseHughes-Stovin syndromeintracardiac masspulmonary artery aneurysmtricuspid valvevasculitis

Identifiers

PMID42165773
PMCPMC13332666

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