Evidence map›Paper›PMID 42165628›Full record

ArticlePlant biotechnology journal2026

Post-Translational Control of TaFT1 by WAPO1 Ubiquitination Shapes Spike Architecture and Yield in Wheat.

Yujie Jiang, Xiongtao Li, Yiqing Wang, Haoran Wang, Zhaoyan Chen, Chaoqun Dong, Xiangqing Liu, Xincheng Wang, Sufang Li, Weilong Guo and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Plant biotechnology journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Yujie JiangState Key Laboratory of High-Efficiency Production of Wheat-Maize Double Cropping, Frontiers Science Center for Molecular Design Breeding, China Agricultural University, Beijing, China.
Xiongtao LiState Key Laboratory of High-Efficiency Production of Wheat-Maize Double Cropping, Frontiers Science Center for Molecular Design Breeding, China Agricultural University, Beijing, China.
Yiqing WangState Key Laboratory of High-Efficiency Production of Wheat-Maize Double Cropping, Frontiers Science Center for Molecular Design Breeding, China Agricultural University, Beijing, China.
Haoran WangState Key Laboratory of High-Efficiency Production of Wheat-Maize Double Cropping, Frontiers Science Center for Molecular Design Breeding, China Agricultural University, Beijing, China.
Zhaoyan ChenInstitute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing, China.
Chaoqun DongState Key Laboratory of High-Efficiency Production of Wheat-Maize Double Cropping, Frontiers Science Center for Molecular Design Breeding, China Agricultural University, Beijing, China.
Xiangqing LiuState Key Laboratory of High-Efficiency Production of Wheat-Maize Double Cropping, Frontiers Science Center for Molecular Design Breeding, China Agricultural University, Beijing, China.
Xincheng WangState Key Laboratory of High-Efficiency Production of Wheat-Maize Double Cropping, Frontiers Science Center for Molecular Design Breeding, China Agricultural University, Beijing, China.
Sufang LiState Key Laboratory of High-Efficiency Production of Wheat-Maize Double Cropping, Frontiers Science Center for Molecular Design Breeding, China Agricultural University, Beijing, China.
Weilong GuoState Key Laboratory of High-Efficiency Production of Wheat-Maize Double Cropping, Frontiers Science Center for Molecular Design Breeding, China Agricultural University, Beijing, China.ORCID https://orcid.org/0000-0001-5199-1359
Yingyin YaoState Key Laboratory of High-Efficiency Production of Wheat-Maize Double Cropping, Frontiers Science Center for Molecular Design Breeding, China Agricultural University, Beijing, China.ORCID https://orcid.org/0000-0003-4122-4118
Mingming XinState Key Laboratory of High-Efficiency Production of Wheat-Maize Double Cropping, Frontiers Science Center for Molecular Design Breeding, China Agricultural University, Beijing, China.ORCID https://orcid.org/0000-0003-4010-4165
Xingguo YeInstitute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing, China.ORCID https://orcid.org/0000-0003-0995-3628
Zhongfu NiState Key Laboratory of High-Efficiency Production of Wheat-Maize Double Cropping, Frontiers Science Center for Molecular Design Breeding, China Agricultural University, Beijing, China.ORCID https://orcid.org/0000-0003-4524-7720
Qixin SunState Key Laboratory of High-Efficiency Production of Wheat-Maize Double Cropping, Frontiers Science Center for Molecular Design Breeding, China Agricultural University, Beijing, China.
Jie LiuState Key Laboratory of High-Efficiency Production of Wheat-Maize Double Cropping, Frontiers Science Center for Molecular Design Breeding, China Agricultural University, Beijing, China.ORCID https://orcid.org/0000-0002-1415-3847

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The florigen protein TaFT1 coordinately regulates heading time and spikelet number per spike (SNS), serving as a key yield determinant in wheat. However, how its stability is post-translationally controlled in the shoot apical meristem remains unclear. Here, we identify the F-box protein WHEAT ORTHOLOG OF APO1 (WAPO1), allelic to a major SNS quantitative trait locus (QSns.cau-7A), as a direct ubiquitin E3 ligase targeting TaFT1 for degradation. A crucial missense mutation (C47F) in the F-box domain of WAPO1 has a significant impact on the SNS. The elite allele WAPO-A1b (from large-spike germplasm AS420, encoding 47F) exhibits stronger binding affinity and ubiquitination activity toward TaFT1 compared with the allele WAPO-A1f (from cultivar Lunxuan987, encoding 47C). Enhanced degradation of TaFT1 by WAPO-A1b in the shoot apical meristem impairs the TaFT1-TaFDL transcriptional complex, thereby downregulating the floral identity gene VRN1/WAP1 and increasing SNS without delaying heading. Notably, the favourable WAPO-A1b allele has been positively selected in modern breeding, and its ectopic activation significantly boosts grain yield in field trials. Our work elucidates a post-translational pathway that fine-tunes spike architecture and highlights WAPO-A1b as a valuable genetic target for high-yield wheat breeding.

Indexed as

Plant ProteinsTriticumGene Expression Regulation, PlantUbiquitinationUbiquitin-Protein LigasesPlant ProteinsUbiquitin-Protein Ligasesspikelet numberTaFT1ubiquitinationWAPO1

Identifiers

PMID42165628
PMCPMC13398888

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.