Evidence map›Paper›PMID 42165544›Full record

ArticleAngewandte Chemie (International ed. in English)2026

Diastereomeric Configuration Modulates Liquid-Liquid Phase Separation and Catalysis in Minimalist Dipeptide Coacervates.

Shuai Peng, Xiaokun Zhang, Xin-Li Shi, Meng Yu, Shoupeng Cao, Ning Gao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shuai PengSchool of Chemistry and Chemical Engineering, Beijing Institute of Technology, Beijing, P. R. China.
Xiaokun ZhangSchool of Chemistry and Chemical Engineering, Beijing Institute of Technology, Beijing, P. R. China.
Xin-Li ShiSchool of Chemistry and Chemical Engineering, Beijing Institute of Technology, Beijing, P. R. China.
Meng YuSchool of Chemistry and Chemical Engineering, Beijing Institute of Technology, Beijing, P. R. China.
Shoupeng CaoCollege of Polymer Science and Engineering, National Key Laboratory of Advanced Polymer Materials, Sichuan University, Chengdu, P. R. China.ORCID https://orcid.org/0000-0002-5856-2407
Ning GaoSchool of Chemistry and Chemical Engineering, Beijing Institute of Technology, Beijing, P. R. China.ORCID https://orcid.org/0000-0002-7855-8739

Funding

Beijing Institute of Technology Research Fund Program and National Key R&D Program of China 2024YFA1212300National Natural Science Foundation of China 22302009National Natural Science Foundation of China 22471016National Natural Science Foundation of China 22572009National Natural Science Foundation of China 52403198National Natural Science Foundation of China W2512058
6 · The paper itself

Abstract

Although coacervates formed via liquid-liquid phase separation (LLPS) of small molecules are widely recognized as plausible protocell models relevant to the origin of life, how the stereochemistry of small molecules influences LLPS remains largely unexplored. Here we report a set of minimalist dipeptide stereoisomers composed of l-proline (

Indexed as

coacervateliquid–liquid phase separationprotocellself‐assemblystereochemistry

Identifiers

PMID42165544
PMCPMC13360630

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.