ArticleJACC. Case reports2026
From Complete Heart Block to Torsades de Pointes: An Axis to Remember.
Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- Electrocardiographic identification of drug effects: QT prolongation, arrhythmias, and clinical monitoring.European journal of clinical pharmacology · 2026Pooled it
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundComplete atrioventricular block is a recognized cause of acquired QT prolongation and Torsades de Pointes. CASE SUMMARY: An 80-year-old woman with no known prior cardiac history presented to the emergency department with acute confusion and altered mental status. There was no reported history of syncope, palpitations or structural heart disease. Baseline electrocardiography demonstrated complete atrioventricular block with a stable junctional escape rhythm and marked corrected QT prolongation (QTc 545 ms). Continuous electrocardiography monitoring revealed sudden-onset polymorphic ventricular tachycardia consistent with Torsades de Pointes. TAKE-HOME MESSAGES: Cardiac memory-induced repolarization abnormalities can trigger Torsades de Pointes in complete complete atrioventricular block despite stable RR intervals. Sudden changes in QRS morphology and axis due to alteration of the escape rhythm during atrioventricular block with persistent T-wave orientation represent an important electrocardiographic warning sign (cardiac memory) because they may lead to further prolongation of the QTc interval and the onset of Torsades de Pointes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.