Evidence map›Paper›PMID 42165462›Full record

ArticleJACC. Case reports2026

Rapid Evolution of Sine-Wave Electrocardiographic Morphology Preceding Cardiac Arrest.

Ahmed Y M El-Medany, Shahid Aziz

Abstract read
In one paragraph

Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ahmed Y M El-MedanyCardiology Department, Southmead Hospital, North Bristol NHS Trust, Bristol, United Kingdom; National Heart and Lung Institute, Imperial College London, London, United Kingdom. Electronic address: a.el-medany24@imperial.ac.uk.
Shahid AzizCardiology Department, Southmead Hospital, North Bristol NHS Trust, Bristol, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

case summaryWe describe the case of a 21-year-old man with severe traumatic brain injury requiring prolonged sedation and vasopressor support, subsequently developing a sudden broad-complex sinusoidal rhythm, and degenerating into electromechanical dissociation and cardiac arrest. A differential diagnosis is discussed. TAKE-HOME MESSAGES: Suspect propofol infusion syndrome in patients receiving high-dose propofol (>4 mg/kg/h) or infusions >48 hours and recognize acidosis, rhabdomyolysis, and hypertriglyceridemia as the principal early warnings, followed by a "Brugada-like" electrocardiogram pattern. Minimize exposure in neurotrauma and intensive care unit patients; once sinusoidal rhythms appear, toxicity is often refractory, and early cessation is the only effective strategy.

Indexed as

anesthesiacritical careelectrocardiogramelectrolyte imbalancehemodynamicspostoperativepropofol infusion syndrometachycardia

Identifiers

PMID42165462
PMCPMC13198141

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.