Evidence map›Paper›PMID 42165180›Full record

ArticleOrthopaedic surgery2026

Biomechanical Effects of Two Types of 3D-Printed Prosthesis Reconstruction After Single-Segmental Total En Bloc Spondylectomy: A Finite Element Analysis.

Jiasheng Chen, Ben Wang, Yang Luo, Xiang Li, Yanchao Tang, Zihe Li, Hua Zhou, Panpan Hu, Xiaoguang Liu, Zhongjun Liu and 1 more

Abstract readComparative Study
In one paragraph

Article in Orthopaedic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Jiasheng ChenDepartment of Orthopaedics, Peking University Third Hospital, Beijing, China.ORCID https://orcid.org/0000-0003-3335-8474
Ben WangDepartment of Orthopaedics, Peking University Third Hospital, Beijing, China.
Yang LuoDepartment of Orthopaedics, Peking University Third Hospital, Beijing, China.
Xiang LiDepartment of Orthopaedics, Peking University Third Hospital, Beijing, China.
Yanchao TangDepartment of Orthopaedics, Peking University Third Hospital, Beijing, China.
Zihe LiDepartment of Orthopaedics, Peking University Third Hospital, Beijing, China.
Hua ZhouDepartment of Orthopaedics, Peking University Third Hospital, Beijing, China.
Panpan HuDepartment of Orthopaedics, Peking University Third Hospital, Beijing, China.ORCID https://orcid.org/0000-0003-4441-2763
Xiaoguang LiuDepartment of Orthopaedics, Peking University Third Hospital, Beijing, China.
Zhongjun LiuDepartment of Orthopaedics, Peking University Third Hospital, Beijing, China.
Feng WeiDepartment of Orthopaedics, Peking University Third Hospital, Beijing, China.ORCID https://orcid.org/0000-0001-8140-0361

Funding

National Key Research and Development Program of China 2023YFC3604400Peking University Third Hospital BYSYDL2023003
6 · The paper itself

Abstract

backgroundTotal en bloc spondylectomy (TES) has emerged as an effective surgical intervention for spinal tumor management. The selection of prosthesis for spinal reconstruction significantly influences patient's postoperative outcomes. This study aims to analyze and compare the biomechanical effects of two types of 3D-printed prostheses and titanium mesh cage (TMC) after TES.

methodsAn intact finite element model (FEM) of L1-L5 segment was developed and validated for simulation. Three L3 TES models were constructed. Model A utilized a 3D-printed prosthesis with an artificial pedicle, model B employed a stand-alone 3D-printed prosthesis, and model C used a TMC. Following parameters were recorded and analyzed to evaluate the biomechanical effects of the three models: (1) the range of motion (ROM), (2) stress of the internal fixation systems, and (3) stress of the L2 inferior endplate and L4 superior endplate.

resultsThe ROMs of all three models were significantly restricted in all directions. Compared with TMC, the implantation of 3D printed prosthesis significantly enhanced spinal stability during extension. The ROMs of models A and B were significantly lower than that of model C during extension, decreasing by 15.2% and 36.4%, respectively. The use of 3D-printed prosthesis for anterior column reconstruction could reduce the stress of prosthesis itself and adjacent endplates. Compared with model C, the maximal decrease in the stress of the endplate of models A and B was 41.5% during flexion and 49.1% during right lateral bending, respectively. In all directions, the stress of the prosthesis was largest in model C, followed by model A and smallest in model B, with statistically significant differences observed.

conclusionAfter single-segmental TES, 3D-printed prosthesis with favorable endplate matching could obtain better biomechanical effects, thereby reducing the risk of internal fixation failure and increasing the postoperative spinal stability.

Indexed as

Lumbar VertebraePlastic Surgery ProceduresPrinting, Three-DimensionalProstheses and ImplantsProsthesis DesignSpinal NeoplasmsBiomechanical PhenomenaFinite Element AnalysisHumansRange of Motion, ArticularSurgical MeshTitaniumTitanium3D‐printed prosthesisbiomechanicsfinite element analysisTESTMC

Identifiers

PMID42165180
PMCPMC13327028

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.