Evidence map›Paper›PMID 42164997›Full record

ArticleBioactive materials2026

Modeling ventricular tachycardia in genetic long QT syndrome using engineered cardiac tissues.

Richard Z Zhuang, Georgia Doufexi, Marc Yehya, Margaretha A J Morsink, Xianghai Liao, Manu Ben-Johny, Gordana Vunjak-Novakovic

Abstract read
In one paragraph

Article in Bioactive materials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Richard Z ZhuangDepartment of Biomedical Engineering, Columbia University, New York, NY, 10027, USA.
Georgia DoufexiDepartment of Biomedical Engineering, Columbia University, New York, NY, 10027, USA.
Marc YehyaDepartment of Physiology and Cellular Biophysics, Columbia University, New York, NY, 10032, USA.
Margaretha A J MorsinkDepartment of Biomedical Engineering, Columbia University, New York, NY, 10027, USA.
Xianghai LiaoDepartment of Biomedical Engineering, Columbia University, New York, NY, 10027, USA.
Manu Ben-JohnyDepartment of Physiology and Cellular Biophysics, Columbia University, New York, NY, 10032, USA.
Gordana Vunjak-NovakovicDepartment of Biomedical Engineering, Columbia University, New York, NY, 10027, USA.

Funding

Mechanism-inspired Strategies to Prevent Pathogenic Late Na Current in Cardiac ArrhythmiasR01HL163576 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Manu Ben Johny · 2023 to 2026
$2.2M
NHLBI NIH HHS R01 HL163576
6 · The paper itself

Abstract

Congenital long QT syndrome (LQTS) predisposes patients to malignant ventricular tachycardias, yet existing

Indexed as

ArrhythmiaCardiac tissue engineeringLong QT syndromeMaturation

Identifiers

PMID42164997
PMCPMC13185772

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.