ArticleEnvironment & health (Washington, D.C.)2026
Unraveling Plastic-Related Chemical Exposures during Pregnancy and Their Associations with Pregnancy Outcomes Using Suspect Screening Analysis.
Article in Environment & health (Washington, D.C.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Socioeconomic Disparities in PFAS Exposure and Susceptibility to Diabetes in Chinese Adults: A Nationwide Cross-Sectional Study.Environment & health (Washington, D.C.) · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
Plastic production has increased sharply in recent decades, releasing numerous chemicals through degradation and additive leaching. We evaluated prenatal exposure to plastic-related chemicals and their associations with pregnancy outcomes using suspect screening analysis in 200 pregnant participants recruited between 13 and 27 weeks of gestation. We detected 441 chemicals in maternal serum samples (9 identified at confidence level 1 and 432 tentatively identified at level 2), using liquid chromatography-quadrupole time-of-flight mass spectrometry (LC-QTOF/MS) with an in-house database of 5267 plastic-related chemicals. We compiled the in-house database with predicted spectra and RTs for 4272 chemicals without available spectra, improving the reliability of suspect screening. Three level 1 chemicals1,3-diphenylguanidine, undecanedioic acid, and 1-octyl-2-pyrrolidoneand 230 level 2 chemicals have not been widely reported, with fewer than 10 publications in the existing literature. Among level 1 chemicals, an interquartile range increase in acetyl tributyl citrate, progesterone, diisobutyl phthalate, 8-hydroxyquinoline, and PFOS was associated with higher odds of preterm birth. PFOS and undecanedioic acid were associated with increased odds of gestational diabetes mellitus (GDM) in logistic regression models adjusted for maternal age and race/ethnicity. We observed associations between four level 2 chemicals and GDM, and eight were associated with gestational hypertension. Exposure levels varied significantly by education, race/ethnicity, and nativity, with higher PFOS observed in participants with higher educational attainment and in non-Hispanic White groups. Our findings highlight novel chemical exposures and their associations with pregnancy complications, raising concerns about gaps in the monitoring of plastic-related chemicals and their potential impacts on maternal health.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.