Oropharyngeal Syphilis Presenting as Tongue Base Ulcer With Lymphadenopathy.

Serena F Pu, Kevin J Carlson, Jonathan R Mark, Benjamin J Rubinstein

Abstract read

In one paragraph

Article in Case reports in otolaryngology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Oropharyngeal Syphilis Presenting as Tongue Base Ulcer With Lymphadenopathy.Case reports in otolaryngology · 2026
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Serena F PuDepartment of Otolaryngology-Head and Neck Surgery, Macon and Joan Brock Virginia Health Sciences EVMS Medical Group at Old Dominion University, Norfolk, Virginia, USA.ORCID https://orcid.org/0000-0002-4627-6403

Kevin J CarlsonDepartment of Otolaryngology-Head and Neck Surgery, Macon and Joan Brock Virginia Health Sciences EVMS Medical Group at Old Dominion University, Norfolk, Virginia, USA.ORCID https://orcid.org/0000-0003-3225-2408

Jonathan R MarkDepartment of Otolaryngology-Head and Neck Surgery, Macon and Joan Brock Virginia Health Sciences EVMS Medical Group at Old Dominion University, Norfolk, Virginia, USA.

Benjamin J RubinsteinDepartment of Otolaryngology-Head and Neck Surgery, Macon and Joan Brock Virginia Health Sciences EVMS Medical Group at Old Dominion University, Norfolk, Virginia, USA.ORCID https://orcid.org/0000-0003-0060-1087

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Within the aerodigestive tract, syphilis presents with varied signs and symptoms, some of which may mimic malignancy or other disease processes. We present the case of a 29-year-old man with otalgia and odynophagia who was found on physical examination and office laryngoscopy to have a 4-cm ulcerative mass of the tongue base and cervical lymphadenopathy. While planning for tissue diagnosis, the patient's serologies revealed positive treponemal antibody testing and elevated rapid plasma reagin (RPR) titers, confirming syphilitic infection, likely representing secondary syphilis. While awaiting operative biopsy, the patient received intramuscular penicillin with complete resolution of the mass and symptoms, and ultimately operative intervention was deferred. While planning for biopsy of suspicious head and neck lesions, clinicians should consider infectious disease workups in patients with risk factors.

Indexed as

lymphadenopathysyphilistongue base ulcer

Identifiers

PMID42164760

DOI10.1155/crot/2673365

PMCPMC13184711

What OpenQuestion holds

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LicenceCC BY

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.