ReviewGland surgery2026
Advanced techniques for mastopexy in patients with ptotic breasts requiring nipple-sparing mastectomy: a narrative review.
Review in Gland surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
0 citing papers in PubMed.
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and Objective: Achieving aesthetically pleasing results in patients with ptotic breasts who require nipple-sparing mastectomy (NSM) is crucial for an enhanced quality of life, however, preservation of the nipple-areola complex (NAC) introduces significant technical challenges. To address this, various surgical approaches and reconstructive timelines have been developed to expand NSM eligibility in patients with breast ptosis. This narrative review aims to synthesize current evidence on these approaches to guide surgical decision-making and patient counseling. Methods: A literature search of PubMed and Embase was conducted to identify studies describing nipple-preserving mastopexy techniques in NSM. Articles detailing surgical approaches, outcomes, and patient selection considerations were reviewed and analyzed to summarize practical guidance for each approach. Key Content and Findings: Five primary surgical strategies for NSM in ptotic breasts were identified. (I) Single-stage nipple-preserving skin-reducing mastectomy (SRM) with concomitant mastopexy and simultaneous reconstruction offers a single operation but increases technical demands. Two-stage approaches with NSM and (II) tissue expander, (III) immediate implant-based reconstruction, or (IV) flap-based reconstruction, followed by secondary mastopexy, offer greater flexibility in NAC positioning and improved vascular safety. Finally, (V) staged nipple-sparing mastectomy (SNSM) utilizes initial mastopexy to optimize nipple position and expand candidacy for NSM and concomitant reconstruction. Understanding these approaches enables tailored surgical planning based on patient anatomy, oncologic safety, and aesthetic goals. Conclusions: Multiple surgical strategies allow safe NAC preservation in patients with ptotic breasts undergoing NSM, improving aesthetic outcomes and expanding eligibility for breast reconstruction. Tailoring the approach to patient anatomy, oncologic considerations, and surgical expertise, combined with careful preoperative planning and multidisciplinary collaboration, can enhance quality of life without compromising oncologic safety.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.