ArticleThe MAK collection for occupational health and safety2024
Tris(1,3-dichloropropyl) phosphate - Determination of bis(1,3-dichloropropyl) phosphate in urine by LC-APCI-ESI-MS/MS: Biomonitoring Method - Translation of the German version from 2024.
Article in The MAK collection for occupational health and safety, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
The working group "Analyses in Biological Materials" of the German Senate Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area (MAK Commission) developed and verified this biomonitoring method for the determination of urinary concentrations of bis(1,3-dichloropropyl) phosphate (BDCPP), which is the major metabolite of tris(1,3-dichloropropyl) phosphate (TDCPP). TDCPP is one of the most commonly used organophosphate flame retardants in cars, residential furniture, and products containing polyurethane foam, and has been detected in dust from private houses, office buildings, and car interiors, suggesting that a majority of the general population is exposed to TDCPP. The aim of this work was to establish a reliable, selective, and sensitive method for the detection of BDCPP in urine. The urine samples are spiked with the internal standard d
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