Evidence map›Paper›PMID 42164641›Full record

ReviewThe MAK collection for occupational health and safety2024

Beryllium and its inorganic compounds - Addendum: Re-evaluation of the BAR: Assessment Values in Biological Material - Translation of the German Version from 2024.

Julia Hiller, Wobbeke Weistenhöfer, Hans Drexler, Andrea Hartwig, MAK Commission

Abstract readReview
In one paragraph

Review in The MAK collection for occupational health and safety, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Julia HillerFriedrich-Alexander-Universität Erlangen-Nürnberg. Institute and Outpatient Clinic of Occupational, Social, and Environmental Medicine Henkestraße 9-11 91054 Erlangen Germany.
Wobbeke WeistenhöferFriedrich-Alexander-Universität Erlangen-Nürnberg. Institute and Outpatient Clinic of Occupational, Social, and Environmental Medicine Henkestraße 9-11 91054 Erlangen Germany.
Hans DrexlerFriedrich-Alexander-Universität Erlangen-Nürnberg. Institute and Outpatient Clinic of Occupational, Social, and Environmental Medicine Henkestraße 9-11 91054 Erlangen Germany.
Andrea HartwigInstitute of Applied Biosciences. Department of Food Chemistry and Toxicology. Karlsruhe Institute of Technology (KIT) Adenauerring 20a, Building 50.41 76131 Karlsruhe Germany.
MAK Commission

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The German Senate Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area (MAK Commission) summarised and re-evaluated the data for beryllium and its inorganic compounds regarding the recommended sampling times for biomonitoring, the derivation of exposure equivalents for carcinogenic substances (EKA) and the biological reference value (BAR) in urine. Only one new study reports data for beryllium in air and urine, but for the same beryllium concentration in air, the corresponding concentration in urine was lower than that given in two older publications. Considering the inconsistent data and questions on the validity of older analytical methods, the data base is not sufficient to derive EKA. The BAR was re-evaluated and a BAR of 0.02 µg/l urine was established based on the data for background exposure. Sampling should be conducted after a steady state has been reached. The data base is not sufficient for the evaluation of a BAR in blood.

Indexed as

7440-41-7BARberylliumbiological reference valueEKAexposure equivalents for carcinogenic substancesUrinurine

Identifiers

PMID42164641
PMCPMC13186128

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.