ArticleUrology case reports2026
Metastatic Leydig cell tumor: A case report and review of the literature.
Article in Urology case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Leydig cell tumors are rare sex cord-stromal neoplasms, mostly benign, with about 10% malignant. A 42-year-old man presented with a 6 cm right testicular mass and sclerotic bone lesions, normal tumor markers, and no lymphadenopathy. Orchidectomy showed a Leydig cell tumor with vascular invasion but no marked atypia. Follow-up was irregular. After 24 months, imaging revealed an 8 × 7.5 cm retroperitoneal mass; biopsy confirmed metastasis. RPLND removed a single involved lymph node. Testosterone fell from >120 nmol/L to 2.30 nmol/L postoperatively. Despite limited risk factors, metastatic disease occurred, highlighting unpredictability, chemoresistance, and importance of surveillance and aggressive surgical management.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.