Evidence map›Paper›PMID 42164539›Full record

ArticleNeuroscience applied2026

The effects of omega-3 fatty acids on Wnt activity in iPSC-derived neural stem cells from adult ADHD patients.

Cristine M Yde Ohki, Natalie M Walter, Louisa C Dury, Letizia Del Campana, Romane Lasmarrigues, Rhiannon V McNeill, Zora Schickardt, Lukasz Smigielski, Susanne Walitza, Sarah Kittel-Schneider and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neuroscience applied, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Cristine M Yde OhkiDepartment of Child and Adolescent Psychiatry and Psychotherapy, Translational Molecular Psychiatry, University Hospital of Psychiatry Zurich, University of Zurich, Wagistrasse 12, 8952, Schlieren, Switzerland.
Natalie M WalterDepartment of Child and Adolescent Psychiatry and Psychotherapy, Translational Molecular Psychiatry, University Hospital of Psychiatry Zurich, University of Zurich, Wagistrasse 12, 8952, Schlieren, Switzerland.
Louisa C DuryDepartment of Child and Adolescent Psychiatry and Psychotherapy, Translational Molecular Psychiatry, University Hospital of Psychiatry Zurich, University of Zurich, Wagistrasse 12, 8952, Schlieren, Switzerland.
Letizia Del CampanaDepartment of Child and Adolescent Psychiatry and Psychotherapy, Translational Molecular Psychiatry, University Hospital of Psychiatry Zurich, University of Zurich, Wagistrasse 12, 8952, Schlieren, Switzerland.
Romane LasmarriguesDepartment of Child and Adolescent Psychiatry and Psychotherapy, Translational Molecular Psychiatry, University Hospital of Psychiatry Zurich, University of Zurich, Wagistrasse 12, 8952, Schlieren, Switzerland.
Rhiannon V McNeillDepartment of Psychiatry, Psychosomatics and Psychotherapy, Center of Mental Health, University of Würzburg, Würzburg, Germany.
Zora SchickardtDepartment of Psychiatry, Psychosomatics and Psychotherapy, Center of Mental Health, University of Würzburg, Würzburg, Germany.
Lukasz SmigielskiDepartment of Child and Adolescent Psychiatry and Psychotherapy, Translational Molecular Psychiatry, University Hospital of Psychiatry Zurich, University of Zurich, Wagistrasse 12, 8952, Schlieren, Switzerland.
Susanne WalitzaDepartment of Child and Adolescent Psychiatry and Psychotherapy, Translational Molecular Psychiatry, University Hospital of Psychiatry Zurich, University of Zurich, Wagistrasse 12, 8952, Schlieren, Switzerland.
Sarah Kittel-SchneiderDepartment of Psychiatry, Psychosomatics and Psychotherapy, Center of Mental Health, University of Würzburg, Würzburg, Germany.
Edna GrünblattDepartment of Child and Adolescent Psychiatry and Psychotherapy, Translational Molecular Psychiatry, University Hospital of Psychiatry Zurich, University of Zurich, Wagistrasse 12, 8952, Schlieren, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The canonical Wnt signaling pathway plays a key role in neurodevelopment and in maintaining cellular homeostasis of the central nervous system in adulthood. It regulates essential processes, such as cell proliferation, differentiation, and synaptogenesis.

Indexed as

Attention-deficit/hyperactivity disorderDocosahexaenoic acidMethylphenidateNeural stem cellsOmega-3Wnt signaling

Identifiers

PMID42164539
PMCPMC13185858

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.