Evidence map›Paper›PMID 42164502›Full record

ArticleFrontiers in immunology2026

CD8 regulatory T cells are a novel type regulatory T cells in the induction of transplantation immune tolerance.

Jin-Can Huang, Yang Zhao, Yu-di Han, Zheng Xia, Guo-Sheng Du, Ren Lang, Lin Zhou

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jin-Can Huang *Devision of Hepatobiliary and Pancreaticosplenic Surgery, Department of General Surgery, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.
Yang Zhao *Devision of Hepatobiliary and Pancreaticosplenic Surgery, Department of General Surgery, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.
Yu-di Han *Department of Plastic and Reconstructive Surgery, The First Medical Center, Chinese PLA General Hospital, Beijing, China.
Zheng XiaZhantansi Department, Central Medical Branch of PLA General Hospital, Beijing, China.
Guo-Sheng DuOrgan Transplantation Center, General Hospital of Northern Theater Command, Shenyang, China.
Ren LangDevision of Hepatobiliary and Pancreaticosplenic Surgery, Department of General Surgery, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.
Lin ZhouDevision of Hepatobiliary and Pancreaticosplenic Surgery, Department of General Surgery, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Regulatory T cells (Tregs) play an essential role in transplantation immune tolerance. Although CD4 Methods: Mesenchymal stem cell-derived tolerogenic dendritic cells (tolDCs) were adoptively infused in a rat liver transplantation model. The frequencies of CD4 Results: Adoptive infusion of tolDCs significantly prolonged graft survival in the rat liver transplantation model. Increased frequencies of CD4 Conclusion: CD8

Indexed as

CD8-Positive T-LymphocytesLiver TransplantationT-Lymphocytes, RegulatoryTransplantation ToleranceAdoptive TransferAnimalsDendritic CellsGraft RejectionGraft SurvivalMaleRatsRats, Inbred Lewdendritic cellsFoxp3immune toleranceregulatory T cellstransplantation

Identifiers

PMID42164502
PMCPMC13183572

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.