ReviewFrontiers in immunology2026
Obinutuzumab-induced acute thrombocytopenia and leukopenia in ANCA-associated glomerulonephritis: case report and literature review.
Review in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Haematological toxicity associated with antineoplastic drugs: a pharmacovigilance analysis based on the FDA adverse event reporting system database.Frontiers in immunology · 2026Article
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3 authors.
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Abstract
Obinutuzumab is a humanized type II anti-CD20 monoclonal antibody with enhanced antibody-dependent cellular cytotoxicity. It is widely used in B-cell malignancies and is increasingly being explored in autoimmune diseases such as lupus nephritis. The main adverse effects include infusion reactions and cytopenias. Among these, obinutuzumab-induced acute thrombocytopenia (OIAT) is a rare but potentially life-threatening complication. However, OIAT has been reported almost exclusively in patients with hematologic malignancies; data in autoimmune diseases remain limited. We report a 55-year-old male with anti-neutrophil cytoplasmic antibody-associated glomerulonephritis who developed acute severe thrombocytopenia and leukopenia shortly after the second dose of obinutuzumab, which was given due to rituximab intolerance. His platelet count (PLT) dropped from 121 × 10
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