Evidence map›Paper›PMID 42164493›Full record

ReviewFrontiers in immunology2026

Research progress in the inhibitory mechanisms of traditional Chinese medicine therapies against influenza A.

Mingjiang Liu, Shitong Han, Ninghao Shi, Tao Zhang, Chenglong Yu, Chen Mei, Xiaolong Xu

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mingjiang Liu *College of Veterinary Medicine, Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, Yangzhou, China.
Shitong Han *College of Veterinary Medicine, Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, Yangzhou, China.
Ninghao ShiCollege of Veterinary Medicine, Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, Yangzhou, China.
Tao ZhangCollege of Veterinary Medicine, Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, Yangzhou, China.
Chenglong YuCollege of Veterinary Medicine, Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou University, Yangzhou, China.
Chen MeiInstitute of Animal Husbandry and Veterinary Medicine, Beijing Academy of Agriculture and Forestry Sciences, Beijing, China.
Xiaolong XuBeijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Influenza A, an acute or subacute respiratory infectious disease caused by the influenza A virus (IAV), affects humans and animals, and poses a serious threat to public health. Currently, IAV prevention and treatment rely primarily on antiviral drugs and nebulization therapy. Although these methods offer rapid efficacy, prolonged or excessive use often induces drug resistance and sequelae, and has high costs. Throughout China's history, traditional Chinese medicine (TCM) has repeatedly resisted major epidemics, and substantially contributed to the survival and cultural continuity of the Chinese nation. Modern medical research has demonstrated that certain traditional Chinese medicinal formulas or their primary active constituents exhibit significant antiviral activity and immunomodulatory effects. Consequently, exploring the antiviral mechanisms of TCM or their active components, alongside their synergistic application with influenza vaccines and existing antiviral drugs, could enable novel approaches and research directions to achieve influenza prevention and control. This article reviews the current status of IAV transmission, as well as progress in modern medical research in influenza A prevention and treatment with TCMs or their active constituents.

Indexed as

Antiviral AgentsDrugs, Chinese HerbalInfluenza A virusInfluenza, HumanMedicine, Chinese TraditionalAnimalsHumansAntiviral AgentsDrugs, Chinese Herbalantiviral activityimmunomodulationinfluenza Ainhibition mechanismtraditional Chinese medicine

Identifiers

PMID42164493
PMCPMC13183804

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.