Evidence map›Paper›PMID 42164486›Full record

ArticleFrontiers in immunology2026

Parenteral neonatal priming followed by heterologous mucosal booster favors IgM

Poorya Foroutan Pajoohian, Audur Anna Aradottir Pind, Jenny Lorena Molina Estupiñan, Dennis Christensen, Gabriel Kristian Pedersen, Thorunn A Olafsdottir, Ingileif Jonsdottir, Stefania P Bjarnarson

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Poorya Foroutan PajoohianFaculty of Medicine, Biomedical Center, School of Health Sciences, University of Iceland, Reykjavik, Iceland.
Audur Anna Aradottir PindFaculty of Medicine, Biomedical Center, School of Health Sciences, University of Iceland, Reykjavik, Iceland.
Jenny Lorena Molina EstupiñanFaculty of Medicine, Biomedical Center, School of Health Sciences, University of Iceland, Reykjavik, Iceland.
Dennis ChristensenCenter for Vaccine Research, Statens Serum Institut, Copenhagen, Denmark.
Gabriel Kristian PedersenCenter for Vaccine Research, Statens Serum Institut, Copenhagen, Denmark.
Thorunn A OlafsdottirFaculty of Medicine, Biomedical Center, School of Health Sciences, University of Iceland, Reykjavik, Iceland.
Ingileif JonsdottirFaculty of Medicine, Biomedical Center, School of Health Sciences, University of Iceland, Reykjavik, Iceland.
Stefania P BjarnarsonFaculty of Medicine, Biomedical Center, School of Health Sciences, University of Iceland, Reykjavik, Iceland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Early-life vaccinations often yield short-lived antibody (Ab) responses due to limited germinal center (GC) reaction and plasma cell (PC) survival. The aim of the study was to assess how vaccine delivery routes (homologous versus heterologous) in mice shape early-life GC dynamics and outputs. 14 days post-booster immunization, spleen, cervical (CLN), and inguinal (ILN) lymph nodes were analyzed for GC B cells, T follicular helper (T

Indexed as

B-LymphocytesImmunoglobulin MImmunologic MemoryMemory B CellsPlasma CellsAnimalsAnimals, NewbornB-Cell Maturation AntigenCell DifferentiationFemaleGerminal CenterImmunization, SecondaryMiceMice, Inbred C57BLB-Cell Maturation AntigenImmunoglobulin Mgerminal centermemory B cellneonatal immunizationplasma cellsprime-boost immunization

Identifiers

PMID42164486
PMCPMC13183861

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.