ArticleDEN open2027
Patient Characteristics Associated With Preference for 480-mL Oral Sodium Sulfate: A Prospective Clinical Study on Bowel Cleansing Efficacy and Taste Acceptability for Total Colonoscopy.
Article in DEN open, 2027. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and Aims: Oral sulfate solutions (OSSs) are used for low-volume bowel preparation but have a distinctive bitter taste. This study evaluated the efficacy and tolerability of OSSs compared with polyethylene glycol plus ascorbate (PEG-ASC) and identified patient factors associated with favorable acceptability. Methods: In this prospective single-center study, patients undergoing colonoscopy using OSSs who had used PEG-ASC for a previous colonoscopy within 2 years were enrolled. Cleansing quality (Boston Bowel Preparation Scale [BBPS]), ingested volume, adverse events, patient preference, and taste acceptability were assessed. Outcomes were also compared between elderly (≥75 years) and non-elderly patients. Results: Among 263 patients, 98% achieved satisfactory cleansing (BBPS ≥ 6). Overall, 54% preferred OSS for their next procedure. Multivariate analysis identified favorable taste acceptability as the strongest predictor of preference (odds ratio [OR], 4.88). Favorable taste acceptability tended to be associated with male sex (OR, 1.58; Conclusions: OSS provided high-quality cleansing with a reduced intake volume. Elderly patients tended to have favorable taste acceptability for OSS, and effective cleansing was achieved with even lower total fluid intake and fewer adverse events. OSS represents an advantageous bowel preparation option for the aging population. Trial Registration: UMIN-CTR: UMIN000052571.
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