ArticleGastroenterology report2026
Current status and challenges of colorectal cancer screening program in Guangzhou, China: a population-based study.
Article in Gastroenterology report, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Colorectal cancer (CRC) remains a major public health burden. In 2015, a large-scale population-based CRC screening program was launched in Guangzhou for residents aged 45-74 years. This study assessed the program's performance during 2015-2023 to inform future strategies. Methods: A cross-sectional analysis was conducted by using data from 575,843 first-time participants. High-risk individuals were identified through a risk assessment questionnaire combined with fecal immunochemical test (FIT), with positives referred for colonoscopy. Statistical analyses were weighted according to the 2020 Guangzhou census population. Passive follow-up was performed via the Guangzhou Cancer Registration System, enabling estimation of true positives and false negatives. Group differences were examined by using the Results: Of 575,843 participants, 83,590 (14.52%; weighted, 14.55%) were assessed as high-risk. Among them, 22,157 (26.51%; weighted, 28.17%) completed colonoscopy. Overall, 915 CRC cases were detected. Higher colonoscopy adherence was associated with higher education, family history of CRC, anorectal symptoms, and financial allowance. Lesions were found to be more common in older individuals, men, and those with positive FIT. More low-risk lesions and fewer early- and mid/late-stage CRCs were found during the second round of screening (2021-2023) than during the first round of screening (2015-2017). Passive follow-up identified 233 CRCs within 1 year among initially screening-negative participants. Conclusions: This study demonstrated the feasibility of a two-step CRC screening strategy in Guangzhou and its effectiveness in detecting early lesions. However, poor adherence to follow-up colonoscopy remains a key limitation. Targeted interventions-including health education, system-level support, and appropriate financial incentives-are essential to improve compliance and overall program effectiveness.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.