Evidence map›Paper›PMID 42164420›Full record

ArticleToxicology reports2026

Toxicological profiling and health hazard characterization of pesticides widely used in Tanzania unmarked.

Jones A Kapeleka, Aiwerasia Ngowi

Abstract read
In one paragraph

Article in Toxicology reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jones A KapelekaTanzania Plant Health and Pesticides Authority (TPHPA), Arusha, Tanzania.
Aiwerasia NgowiDepartment of Environmental and Occupational Health, Muhimbili University of Health and Allied Sciences (MUHAS), Dar-es-Salaam, Tanzania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The toxicity of many pesticides to humans and their contribution to various health problems continue to increase rapidly. This study highlights the inherent effects of highly hazardous pesticides (HHPs) used in smallholder agricultural systems. Primary data were collected through interviews, while secondary data came from scientific databases and search engines, including Scopus, PubMed, Web of Science, and Google Scholar. A total of 810 respondents participated in the study. The characterization of health and environmental impacts was based on the active ingredients mostly used, especially those that have been discontinued, withdrawn, or banned in other regions due to their harmfulness. The toxicological profile focused on effects such as neurotoxicity, reproductive toxicity, developmental toxicity, immunotoxicity, genotoxicity, carcinogenicity, and endocrine disruption. Results show that over 150 active ingredients are used in pesticides, some of which are classified as highly hazardous pesticides (HHPs). Key pesticides like lambda-cyhalothrin, glyphosate, 2,4-dimethylamine, mancozeb, chlorpyrifos, profenofos, cypermethrin, carbendazim, paraquat, atrazine, and carbofuran dominate smallholder farming. The widespread use of HHPs in Tanzania, under current conditions, constitutes a significant public health and environmental crisis, suggesting that knowledge does not always translate into safe practices. The combination of inherently hazardous pesticides, inadequate regulatory oversight, and unsafe handling practices creates a perfect storm of exposure. Strengthening laws and regulations around pesticide registration, post-market monitoring, and enforcement is urgently needed to protect human health and the environment.

Indexed as

CarbamatesHighly Hazardous PesticidesHuman HealthOrganophosphatesPesticide ExposurePesticide PoisoningPesticide Toxicity

Identifiers

PMID42164420
PMCPMC13186087

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.