Evidence map›Paper›PMID 42164361›Full record

ArticleTranslational andrology and urology2026

Pediatric non-rhabdomyosarcoma bladder tumors (NRBTs): a 20-year retrospective longitudinal cohort study at a tertiary referral center.

Yangyue Huang, Yiwei Fang, Hongcheng Song, Weiping Zhang, Ning Sun, Wenwen Han, Guannan Wang, Chao Liu

Abstract read
In one paragraph

Article in Translational andrology and urology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Yangyue Huang *Department of Pediatric Urology, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China.
Yiwei Fang *Department of Pediatric Urology, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China.
Hongcheng SongDepartment of Pediatric Urology, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China.
Weiping ZhangDepartment of Pediatric Urology, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China.
Ning SunDepartment of Pediatric Urology, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China.
Wenwen HanDepartment of Pediatric Urology, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China.
Guannan Wang *Department of Pediatric Urology, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China.
Chao Liu *Department of Pediatric Urology, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Pediatric non-rhabdomyosarcoma bladder tumors (NRBTs) encompass a diverse spectrum of tumors with low incidence rates. This study aims to improve understanding and contribute to the management of pediatric NRBTs. Methods: We retrospectively enrolled patients with primary pediatric NRBTs diagnosed and treated at our center between 2003 and 2023. Clinicodemographic and clinicopathological data were collected. NRBTs were classified into four categories: urothelial tumors (UTs), mesenchymal tumors (MTs), neuroendocrine tumors (NTs), and rare types of bladder tumors (rBTs). Intergroup comparative analyses were conducted. Results: We identified 51 cases of NRBTs. Four categories encompassed: UTs (n=25, 49.0%), MTs (n=17, 33.3%) and NTs (n=5, 9.8%), and rBTs (n=4, 7.8%). No cases of UTs were identified below the age of 3 years. Comparative analyses demonstrated significant intergroup differences in preoperative anemia prevalence (P=0.02) and tumor size (P<0.001). Total 45 patients (88.2%) completed follow-up, with a median duration of 64 months [interquartile range (IQR), 28-113 months]. Local recurrences were identified in 5 cases (11.1%), among whom 1 case (2.0%) succumbed to local recurrence and disease progression. Conclusions: Pediatric NRBTs demonstrate generally favorable clinical outcomes. Age under 3 years, preoperative anemia or a maximum tumor diameter exceeding 3 cm should raise a strong suspicion for non-UTs bladder tumors. Postoperative surveillance protocols can incorporate urinary ultrasonography (US) as a non-invasive monitoring tool.

Indexed as

childrenmesenchymal tumors (MTs)neuroendocrine tumors (NTs)Non-rhabdomyosarcoma bladder tumors (NRBTs)urothelial tumors (UTs)

Identifiers

PMID42164361
PMCPMC13184329

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