Evidence map›Paper›PMID 42164285›Full record

ArticleRSC advances2026

Copper-hollow mesoporous polydopamine-polyacrylic acid nanoplatform enabling photoacoustic imaging-guided photothermal/chemodynamic therapy for osteosarcoma.

Haoyu Sun, Zeping Liu, Bowen Chen, Yunkai Bao, Fenghua Li, Rui Gu, Zhenxin Wang

Abstract read
In one paragraph

Article in RSC advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Haoyu SunDepartment of Orthopaedic Surgery, China-Japan Union Hospital of Jilin University Changchun 130033 PR China gurui@jlu.edu.cn.ORCID https://orcid.org/0009-0005-1898-8410
Zeping LiuDepartment of Orthopaedic Surgery, China-Japan Union Hospital of Jilin University Changchun 130033 PR China gurui@jlu.edu.cn.
Bowen ChenDepartment of Thyroid Surgery, General Surgery Center, The First Hospital of Jilin University Changchun 130021 Jilin China.
Yunkai BaoKey Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences Changchun 130022 Jilin China.
Fenghua LiKey Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences Changchun 130022 Jilin China.ORCID https://orcid.org/0000-0003-2994-8738
Rui GuDepartment of Orthopaedic Surgery, China-Japan Union Hospital of Jilin University Changchun 130033 PR China gurui@jlu.edu.cn.ORCID https://orcid.org/0009-0001-4652-5561
Zhenxin WangKey Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences Changchun 130022 Jilin China.ORCID https://orcid.org/0000-0002-1908-9848

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteosarcoma (OS) is an extremely destructive and lethal primary bone cancer, and its treatment remains a great challenge. Herein, a nanoplatform (HMPDA-Cu@PAA) was constructed by loading copper ions into hollow mesoporous polydopamine (HMPDA) and subsequently coating with polyacrylic acid (PAA), which exhibits dual responsiveness to the tumor microenvironment (TME) and exogenous 808 nm near-infrared (NIR) laser irradiation. The mutual conversion of Cu

Identifiers

PMID42164285
PMCPMC13185696

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.