SynthesisFrontiers in medicine2026
Robot-assisted simple prostatectomy vs. laser enucleation of the prostate for large-volume benign prostatic hyperplasia (BPH, ≥80 mL): a systematic review and meta-analysis.
Synthesis in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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5 authors.
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Abstract
Background: Robot-assisted simple prostatectomy (RASP) and laser enucleation of the prostate (LEP) are established surgical options for the treatment of large-volume benign prostatic hyperplasia (BPH); however, consensus regarding the superiority of one technique over the other has not been established. This study aimed to comprehensively compare the perioperative efficiency, safety, and functional outcomes of RASP and LEP. Methods: We conducted a comprehensive search of four databases (PubMed, Embase, Web of Science, and Scopus) to identify studies comparing RASP and LEP in large-volume BPH. Pooled and subgroup analyses were performed using Stata MP 18 and Review Manager 5.4.0. Results: Fifteen studies (2,231 patients, 763 RASP and 1,468 LEP) were included in the analysis. LEP was associated with shorter operative time and catheterization duration than RASP. Hospital stay was reduced with thulium fiber laser enucleation of the prostate (ThuLEP; mean difference [MD] 2.43, 95% confidence interval [CI] 1.52-3.34, Conclusion: Both RASP and LEP may be safe and effective surgical options for large-volume BPH. LEP may be associated with faster perioperative recovery, whereas RASP may reduce the incidence of UI and potentially improve long-term symptom control. Given the observational design of included studies, heterogeneity across cohorts, and limitations of retrospective evidence, these findings should be interpreted with caution, and tailored surgical strategies are recommended.
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