ArticleFrontiers in medicine2026
Retrospective analysis of the clinical efficacy of topical hyaluronic acid in promoting skin recovery and reducing inflammatory reactions after fractional laser treatment.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Fractional laser treatment is widely used to improve skin problems such as scars and photoaging; however, it is prone to causing adverse reactions such as erythema and edema after the procedure. Topical hyaluronic acid can provide moisturizing, reparative, anti-inflammatory, and healing effects, but related research remains limited. Objective: This study aimed to explore the effectiveness and safety of topical hyaluronic acid dressings in promoting skin recovery and reducing inflammatory reactions after fractional laser surgery, thereby providing a reference for clinical postoperative care. Method: This study is a retrospective comparative cohort study, with data collection and analysis conducted by researchers who did not participate in patient treatment. A total of 113 patients who underwent fractional laser treatment in our hospital from January 2021 to January 2025 were included. Patients were categorized into two groups based on their postoperative care regimen documented in medical records: the Routine Care (RC) group ( Results: The HA group had significantly shorter times to erythema disappearance and scab shedding than the RC group ( Conclusion: The combination of hyaluronic acid dressings with routine nursing care was associated with improved skin recovery and reduced inflammatory reactions after fractional laser surgery in this observational comparative cohort, suggesting potential clinical value for postoperative management.
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