ArticleFrontiers in neurology
Reliability and minimal clinically important differences of gait characteristics in peripheral vestibular disorders.
Article in Frontiers in neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: Sensory gait ataxia is a core feature of chronic peripheral vestibular disorders, leading to impaired mobility, reduced quality of life, and increased fall risk. Quantitative gait metrics capturing this deficit are valuable endpoints for clinical trials, yet data on their reliability and clinically meaningful change remain limited. Methods: Gait was recorded in 60 patients with chronic bilateral ( Results: Self-selected walking showed good-to-excellent reliability across all domains except asymmetry, with similar results for slow and eyes-closed walking. Clinically meaningful changes were linked to faster gait, longer swing phases, lower variability and asymmetry, and narrower stride width, enabling MCID determination for each metric. Conclusion: Quantitative gait metrics can be reliably assessed in peripheral vestibular disorders and provide robust, clinically relevant endpoints for future intervention studies.
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