Evidence map›Paper›PMID 42164111›Full record

ArticleBJUI compass2026

Using an artificial intelligence-based device to investigate pain outcomes in robotic prostatectomy at low pressure pneumoperitoneum: The RALP clinical trial.

Nikhil Vasdev, Lawrence Isherwood, Matthew Feyissa, Neil Spencer, Charo Roxas-Saguil, Ashling Jonsson, Karen Irvine, David Wellsted, Sarah King, Justin Daniels and 9 more

Abstract read
In one paragraph

Article in BJUI compass, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Nikhil VasdevHertfordshire and Bedfordshire Urological Cancer Centre, Department of Urology, Lister Hospital East and North Hertfordshire Teaching NHS Trust Stevenage UK.ORCID https://orcid.org/0000-0002-3966-5734
Lawrence IsherwoodHertfordshire and Bedfordshire Urological Cancer Centre, Department of Urology, Lister Hospital East and North Hertfordshire Teaching NHS Trust Stevenage UK.
Matthew FeyissaHertfordshire and Bedfordshire Urological Cancer Centre, Department of Urology, Lister Hospital East and North Hertfordshire Teaching NHS Trust Stevenage UK.ORCID https://orcid.org/0009-0001-2135-3169
Neil SpencerDepartment of Applied Statistics, Hertfordshire Business School University of Hertfordshire Hatfield UK.
Charo Roxas-SaguilHertfordshire and Bedfordshire Urological Cancer Centre, Department of Urology, Lister Hospital East and North Hertfordshire Teaching NHS Trust Stevenage UK.
Ashling JonssonHertfordshire and Bedfordshire Urological Cancer Centre, Department of Urology, Lister Hospital East and North Hertfordshire Teaching NHS Trust Stevenage UK.
Karen IrvineThe Centre for Health Sciences and Clinical Research University of Hertfordshire Hatfield UK.
David WellstedThe Centre for Health Sciences and Clinical Research University of Hertfordshire Hatfield UK.
Sarah KingHertfordshire and Bedfordshire Urological Cancer Centre, Department of Urology, Lister Hospital East and North Hertfordshire Teaching NHS Trust Stevenage UK.
Justin DanielsHertfordshire and Bedfordshire Urological Cancer Centre, Department of Urology, Lister Hospital East and North Hertfordshire Teaching NHS Trust Stevenage UK.
Louise PeacockHertfordshire and Bedfordshire Urological Cancer Centre, Department of Urology, Lister Hospital East and North Hertfordshire Teaching NHS Trust Stevenage UK.
Toral OdedraHertfordshire and Bedfordshire Urological Cancer Centre, Department of Urology, Lister Hospital East and North Hertfordshire Teaching NHS Trust Stevenage UK.
Phillip SmithHertfordshire and Bedfordshire Urological Cancer Centre, Department of Urology, Lister Hospital East and North Hertfordshire Teaching NHS Trust Stevenage UK.
Prokar DasguptaDepartment of Urology Guy's and St Thomas' Hospitals NHS Trust and Faculty of Life Sciences and Medicine, Kings College London London UK.
Karel DecaesteckerDepartment of Urology AZ Maria Middelares Hospital Ghent Belgium.ORCID https://orcid.org/0000-0003-0767-940X
Prashanth BelavadiDepartment of Anaesthesia, Lister Hospital East and North Hertfordshire Teaching NHS Trust Stevenage UK.
Bhavin ShuklaDepartment of Anaesthesia, Lister Hospital East and North Hertfordshire Teaching NHS Trust Stevenage UK.
Venkat PrasadDepartment of Anaesthesia, Lister Hospital East and North Hertfordshire Teaching NHS Trust Stevenage UK.
Shan Gowrie-MohanDepartment of Anaesthesia, Lister Hospital East and North Hertfordshire Teaching NHS Trust Stevenage UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study aims to investigate any differences in the levels of intra-operative (measured by an artificial intelligence device) and post-operative pain between two different abdominal insufflators (AirSeal vs Stryker) used for a low-pressure pneumoperitoneum robotic prostatectomy. Methods: A prospective randomised controlled clinical study was performed at Lister Hospital, Stevenage. The primary aim was to evaluate the feasibility of recruiting 40 patients with localised prostate cancer who underwent a robotic prostatectomy with either an AirSeal® Insufflation System ( Results: Forty patients were successfully recruited onto the RALP trial with complete 30-day follow-up. AirSeal has fewer significant nociceptive events per recorded hour than Stryker (20.7 vs. 33.5, Conclusions and relevance: In this study, we were able to successfully recruit 40 participants with complete 30-day follow-up. There were advantageous surgical factors and lesser intra-operative nociceptive insult associated with the AirSeal insufflator. Further RCTs are planned with a larger population to investigate the true causality of this relationship.

Indexed as

artificial intelligenceinsufflatorlow pressurepneumo‐peritoneumprostate cancerrobotic prostatectomy

Identifiers

PMID42164111
PMCPMC13183494

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.