Evidence map›Paper›PMID 42164080›Full record

ArticleBioinformatics advances2026

EGGS: Empirical Genotype Generalizer for Samples.

T Quinn Smith, Amatur Rahman, Zachary A Szpiech

Abstract read
In one paragraph

Article in Bioinformatics advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

T Quinn SmithDepartment of Biology, The Pennsylvania State University, University Park, PA 16802, United States.ORCID https://orcid.org/0009-0004-9955-4915
Amatur RahmanDepartment of Biology, The Pennsylvania State University, University Park, PA 16802, United States.ORCID https://orcid.org/0000-0002-9166-1220
Zachary A SzpiechDepartment of Biology, The Pennsylvania State University, University Park, PA 16802, United States.ORCID https://orcid.org/0000-0001-6372-8224

Funding

Population Genetics Methods for Understanding Complex Trait EvolutionR35GM146926 · NIGMS · PENNSYLVANIA STATE UNIVERSITY, THE · PI Zachary Alfano Szpiech · 2022 to 2026
$1.8M
NIGMS NIH HHS R35 GM146926
6 · The paper itself

Abstract

Motivation: We introduce Empirical Genotype Generalizer for Samples (EGGS) which accepts empirical genotypes with missing data and replicates the distribution of missing genotypes along the empirical segment in other replicates. The empirical segment must have a number of sites less than the replicate. In addition, EGGS can remove phase, remove polarization, simulate deamination, simulate sequencing error, create pseudohaploids, and convert between Variant Call Format (VCF), Availability: EGGS is written in the C programming language. Precompiled executables, source code, the manual, and the analysis conducted in the paper are available at https://github.com/TQ-Smith/EGGS.

Identifiers

PMID42164080
PMCPMC13186185

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.