Evidence map›Paper›PMID 42164020›Full record

ArticleFrontiers in cellular neuroscience2026

Identity crisis: exploring the boundaries of cell type identification in the age of single-cell transcriptomics.

Seulkee Yang, Sudeeksha Tyagi, Christian Rosenmund, Melissa A Herman

Abstract read
In one paragraph

Article in Frontiers in cellular neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Seulkee Yang *Institute for Neurophysiology, Charité Universitätsmedizin-Berlin, Berlin, Germany.
Sudeeksha Tyagi *Institute for Neurophysiology, Charité Universitätsmedizin-Berlin, Berlin, Germany.
Christian RosenmundInstitute for Neurophysiology, Charité Universitätsmedizin-Berlin, Berlin, Germany.
Melissa A HermanInstitute for Neurophysiology, Charité Universitätsmedizin-Berlin, Berlin, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The rise of single-cell transcriptomics and comprehensive reference atlases promised a unifying molecular framework to classify cell identity. Yet transcriptomic identities are often interpreted outside the environmental contexts in which they arise. Here, we analyzed primary cortical cultures, which lack native tissue architecture, to compare their transcriptional profiles to multiple

Indexed as

cell identity classificationcortical neuronal identityin vitro vs in vivoprimary neuronal cell culturesingle-cell transcriptomics

Identifiers

PMID42164020
PMCPMC13183566

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.