ArticlePolish journal of radiology2026
Quantitative assessment of thoracic morphometry in interstitial lung diseases: a CT-based comparison of nonspecific interstitial pneumonia, usual interstitial pneumonia, and healthy control.
Article in Polish journal of radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Purpose: This study aimed to quantitatively assess thoracic morphometry using thoracic computed tomography (CT) in patients with nonspecific interstitial pneumonia (NSIP), usual interstitial pneumonia (UIP), and healthy controls, and to determine whether morphometric parameters can differentiate between interstitial lung disease (ILD) subtypes. Material and methods: A retrospective, cross-sectional study was conducted involving 180 participants (60 NSIP, 60 UIP, and 60 healthy controls). Standardised thoracic CT scans were analysed at 3 thoracic levels (T3, T6, and T9). The anteroposterior (AP) and transverse (T) thoracic diameters were measured, and their ratios (AP/T) were calculated. Results: Significant intergroup differences were observed in thoracic dimensions, mainly at the upper thoracic level (T3). UIP patients showed smaller AP and transverse diameters than NSIP and controls ( Conclusions: Quantitative CT-based thoracic morphometry reveals distinct structural differences among ILD subtypes. Patients with UIP show reduced upper thoracic dimensions consistent with restrictive remodeling, whereas NSIP demonstrates relatively preserved thoracic configuration. CT-derived thoracic diameters represent simple, reproducible, and cost-effective imaging biomarkers that may complement conventional pattern analysis and support objective disease assessment.
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