Evidence map›Paper›PMID 42163790›Full record

Observational studyDeutsches Arzteblatt international2026

Regional Variation in the Prevalence of Frailty Among Very Old Adults in Germany: Findings of the Nationwide Study "Old Age in Germany" (D80+).

Manuel Amthor, Elisabeth Zwinge, Maximilian König

Abstract readObservational Study
In one paragraph

Observational study in Deutsches Arzteblatt international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

3 authors.

Manuel AmthorDepartment of Internal Medicine D – Geriatrics, University Medicine Greifswald, Greifswald, Germany
Elisabeth ZwingeDepartment of Internal Medicine D – Geriatrics, University Medicine Greifswald, Greifswald, Germany
Maximilian KönigDepartment of Internal Medicine D – Geriatrics, University Medicine Greifswald, Greifswald, Germany

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFrailty is a key geriatric syndrome that determines the care of the affected old adults. The goal of this study is to quantify the prevalence and regional distribution of frailty among very old adults in Germany, on which no nationwide data have been available to date.

methodsWe analyzed data obtained by questionnaire from 9855 persons aged 80 and above in the nationwide D80+ survey. Frailty was operationalized with a frailty index (cutoff value: ≥0.25) encompassing 40 items. Its prevalence was estimated with logistic regression adjusted for age and sex. Socio-economic factors (education, income, type of residence) were additionally taken into account in an extended model.

resultsThe overall prevalence of frailty was 54.5% (95% confidence interval [53.2; 55,7]). Frail persons were more commonly female, widowed, living in a nursing or old-age home, and of lower socio-economic status. Regional variation was identified that persisted after the additional consideration of socio-economic factors and type of residence. The two federal states with the lowest prevalence were Bremen (42.6%) and Schleswig-Holstein (49.9%); those with the highest prevalence were Brandenburg (59.7%) and Saxony (60.8%).

conclusionFrailty is highly prevalent among very old adults in general, with regional disparities that imply an effect of region-specific factors. The awareness of regional variability and a better understanding of its causes can be used to inform future public health strategies and regional care planning.

Indexed as

Frail ElderlyFrailtyAged, 80 and overAge DistributionFemaleGeriatric AssessmentGermanyHumansMalePrevalenceRisk FactorsSex DistributionSocioeconomic Factors

Identifiers

PMID42163790
PMCPMC13459140

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.