ArticleVox sanguinis2026
Preventing overfilling of blood bags to reduce clot formation and improve donor safety.
Article in Vox sanguinis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Preventing overfilling of blood bags to reduce clot formation and improve donor safety.Vox sanguinis · 2026Article
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Authors and funding
7 authors.
Funding
Abstract
BACKGROUND AND
objectivesOverfilling of blood bags is common in low-resource settings, causing clot formation, donor and recipient risks and blood wastage. This study assessed overfilling prevalence and evaluated a low-cost intervention to mitigate it. MATERIALS AND
methodsWe conducted a prospective study across six blood banks in Kano, Nigeria, weighing 131 blood bags and examining clot formation in 688 consecutive units. A simple, manual measuring and mixing (MeMi) device was developed and implemented to prevent overfilling.
resultsBefore intervention, 129/131 blood bags (98.5%) exceeded the 612 g upper limit (mean: 711 g; range: 560-888 g). Systematic assessment revealed macroclots in 72/688 bags (10.5%; 95% confidence interval [CI]: 8.18-12.76). After MeMi use, 658/723 bags (91%) met the target weight (500-612 g), while 2 were overweight (629 g, 639 g) and 63 underweight (265-499 g). Clot incidence dropped to 1.9% (95% CI: 0%-5.1%).
conclusionOverfilling of blood bags poses serious safety concerns in low-resource settings. The MeMi device provides a practical, low-cost mechanical solution without needing electricity. Locally producible for ~€15, it significantly reduces overfilling and clotting. This improves safety for donors and recipients. Its simplicity and affordability make it highly scalable across regions like sub-Saharan Africa.
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