Evidence map›Paper›PMID 42163393›Full record

ArticleBMC research notes2026

Associations of weight loss, low serum albumin, and their combination with mortality risk in older adults receiving home medical care.

Tomoko Yano, Naoko Murakami, Yuka Fukata, Chika Nakamura, Chihiro Anzai, Yumiko Nako, Eriko Koujiya, Toshinori Nakamura, Atsushi Hirotani, Toshio Fukuda and 13 more

Abstract read
In one paragraph

Article in BMC research notes, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Tomoko YanoDivision of Health Sciences, Graduate School of Medicine, Osaka University, Suita, Japan. t-yano@otemae.ac.jp.
Naoko MurakamiDivision of Health Sciences, Graduate School of Medicine, Osaka University, Suita, Japan.
Yuka FukataDivision of Health Sciences, Graduate School of Medicine, Osaka University, Suita, Japan.
Chika NakamuraDivision of Health Sciences, Graduate School of Medicine, Osaka University, Suita, Japan.
Chihiro AnzaiDivision of Health Sciences, Graduate School of Medicine, Osaka University, Suita, Japan.
Yumiko NakoDivision of Health Sciences, Graduate School of Medicine, Osaka University, Suita, Japan.
Eriko KoujiyaDivision of Health Sciences, Graduate School of Medicine, Osaka University, Suita, Japan.
Toshinori NakamuraNakamura Clinic, Osaka, Japan.
Atsushi HirotaniHirotani Clinic, Osaka, Japan.
Toshio FukudaFukuda Clinic, Osaka, Japan.
Michio TamataniTamatani Clinic, Osaka, Japan.
Yoshinari OkudaOkuda Clinic, Osaka, Japan.
Masashi IkushimaIkushima Clinic, Itami, Hyogo, Japan.
Yoshichika BabaBaba Clinic, Osaka, Japan.
Masahiro NaganoNagano Clinic, Osaka, Japan.
Yukio NakamuraYukokai Nakamura Clinic, Osaka, Japan.
Taizo WadaDivision of Health Sciences, Graduate School of Medicine, Osaka University, Suita, Japan.
Yuya AkagiDivision of Health Sciences, Graduate School of Medicine, Osaka University, Suita, Japan.
Kayo GodaiDivision of Health Sciences, Graduate School of Medicine, Osaka University, Suita, Japan.
Michiko KidoDivision of Health Sciences, Graduate School of Medicine, Osaka University, Suita, Japan.
Mai KabayamaDivision of Health Sciences, Graduate School of Medicine, Osaka University, Suita, Japan.
Hiromi RakugiDivision of Health Sciences, Graduate School of Medicine, Osaka University, Suita, Japan.
Kei KamideDivision of Health Sciences, Graduate School of Medicine, Osaka University, Suita, Japan.

Funding

JSPS KAKENHI 19K07888JSPS KAKENHI 19K11138JSPS KAKENHI 20K10975
6 · The paper itself

Abstract

objectiveThis study aimed to examine the associations of weight loss, low serum albumin levels, and their combination with 2-year mortality risk in older adults receiving home medical care.

resultsParticipants from the Osaka Home Care Registry Study aged 65 or older were classified into two groups: low and high baseline serum albumin levels, and stratified into those with 5% weight loss and weight maintenance after 1 year. Low serum albumin and weight loss were present in 21.8% and 20.8% of participants, respectively. In multivariable Cox proportional hazards analysis, combinations involving low serum albumin were significantly associated with mortality. Participants with weight maintenance and low serum albumin (HR = 6.89, 95%CI = 2.06-23.02) and those with weight loss and low serum albumin (HR = 19.06, 95%CI = 4.42-82.14) had a higher mortality risk, whereas weight loss alone was not significant. These findings suggest that evaluating serum albumin together with weight change may help identify high-risk individuals in home medical care.

Indexed as

Home Care ServicesMortalityRegistriesSerum AlbuminWeight LossAgedAged, 80 and overFemaleHumansJapanMaleProportional Hazards ModelsRisk FactorsSerum AlbuminCohort studyHome medical careMortalitySerum albuminWeight loss

Identifiers

PMID42163393
PMCPMC13411735

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.