ArticleJournal of orthopaedic surgery and research2026
Combining arthroscopic microfracture, autologous bone grafting, and PRP injection for the treatment of Hepple IV-V stage osteochondral lesions of talus.
Article in Journal of orthopaedic surgery and research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
purposeThe purpose of this study was to evaluate the clinical and radiological outcomes of arthroscopic autologous cancellous bone grafting combined with platelet-rich plasma (PRP) injection in patients with osteochondral lesions of talus (OLT).
methodsThis retrospective study was conducted at Xuzhou Renci Hospital from January 2020 to June 2023, including patients was diagnosed with Hepple stage IV or V OLT by magnetic resonance imaging (MRI). All patients underwent arthroscopic debridement and microfracture, autologous cancellous bone grafting, and PRP injection. Preoperative and postoperative assessments were performed using the visual analogue scale (VAS) for pain, the American Orthopaedic Foot & Ankle Society (AOFAS) Ankle-Hindfoot Scale and Kofoed score for ankle function. Radiological outcomes were evaluated by the magnetic resonance observation of cartilage repair tissue (MOCART). A paired sample t-test was used for statistical analysis to compare preoperative and postoperative data, with a P-value < 0.05 was considered statistically significant.
resultsOf the 21 patients with single cystic OLT with a complete set of follow-up data, there were 13 males and 8 females, with a mean age of 49.76 ± 10.24 years, a mean follow-up time of 16.81 ± 2.46 months and a mean illness duration of 12.47 ± 5.51 months. The mean VAS had significant (P < 0.001 decreased from 6 (5, 6) preoperatively to 1 (1, 1.5) at the last follow-up. The mean AOFAS and Kofoed scores significantly (P < 0.001) improved from 63.24 ± 9.81 preoperatively to 89.33 ± 5.47 at the last follow-up and from 28.43 ± 8.77 to 89.14 ± 5.19, respectively. All patients underwent follow-up MRI with a mean MOCART score of 69.10 ± 10.36 at last follow-up. No complications occurred in all patients, and no adverse reactions were observed at the donor knee site.
conclusionArthroscopic microfracture, autologous cancellous bone grafting and PRP injection is a promising technique for treating OLT, with favorable short-term pain relief, functional improvement and a high patient satisfaction rate for Hepple IV-V OLT. It is necessary to conduct large-scale, prospective, randomized controlled trials to further validate the long-term efficacy and safety of this procedure.Keywords Osteochondral lesions of talus (OLT), Arthroscopy, autologous cancellous bone grafting, platelet-rich plasma (PRP).
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.