Evidence map›Paper›PMID 42163302›Full record

ArticleBMC health services research2026

Hospitalization costs and out-of-pocket expenses for stroke patients in mainland China.

Wen-Jun Tu, Mingxin Wang, Yangyi Fan, Xianwei Zeng

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Article in BMC health services research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Wen-Jun TuDepartment of Neurology, Aerospace Center Hospital, Peking University Aerospace School of Clinical Medicine, No.15, Yu Quan Road, Hai Dian District, Beijing, 100049, China. twjun1983@gmail.com.
Mingxin WangDepartment of Head and Neck Vascular Surgery, Shengli Oilffeld Central Hospital, Dongying, Shandong, China.
Yangyi FanDepartment of Neurology, Peking University People's Hospital, Beijing, China.
Xianwei ZengDepartment of Neurosurgery, Rehabilitation Hospital of the National Research Center for Rehabilitation Technical Aids, Beijing, China.

Funding

China Postdoctoral Science Foundation 2019M660921 and 2020T130436National Natural Science Foundation of China 61971011 and 82371348
6 · The paper itself

Abstract

introductionThis study aimed to assess hospitalization expenditures and out-of-pocket burden (OOPB, defined as out-of-pocket expenses [OOPE] divided by disposable annual income multiplied by household size and expressed as a percentage) in patients with stroke in mainland China from 2019 to 2020.

methodsThis research encompassed patients from hospitals jointly affiliated with the Chinese Hospital Quality Monitoring System and the Big Data Observatory Platform for Stroke of China. We focused on individuals hospitalized between 2019 and 2020, who were primarily diagnosed with a stroke, as classified under the ICD-10 codes: ischemic stroke (IS), intracerebral hemorrhage (ICH), and subarachnoid hemorrhage (SAH). We estimated the out-of-pocket rate (OOPR, defined as OOPE divided by hospitalization expenditures expressed as a percentage), high OOPB, and catastrophic healthcare payments (defined as OOPB exceeding 30%) at the national and provincial levels. The correlation between OOPR and in-hospital mortality in different provinces was also examined.

resultsThe database included 7,226,376 stroke patients from 1,599 hospitals, of whom 58.6% were male. The OOPR and OOPB in stroke patients were 32.6% (95% CI, 31.9%-33.3%) and 6.3% (95% CI, 6.1%-6.4%), respectively. For IS and ICH, more than two-thirds (22/32) of China's provinces had an OOPR of over 28.0%, while three-quarters of provinces (24/32) for SAH had an OOPR of over 28.0%. For IS and ICH, none of the provinces had catastrophic healthcare payments, whereas for SAH, over half of the provinces (18/32) did. We analyzed the relationship between OOPR and stroke in-hospital mortality at the provincial level, but the data did not confirm a correlation between the two factors (IS: r=-0.172, P=0.34; ICH: r=0.078, P=0.67; SAH: r=0.041, P=0.82).

conclusionThe acute hospitalization costs and OOPB on stroke patients is significant, with nearly a third of their medical costs paid out-of-pocket. This underscores the pressing necessity to advance the development of a more inclusive healthcare system, particularly in economically challenged regions.

Indexed as

Health ExpendituresHospital CostsHospitalizationStrokeAgedChinaFemaleHospital MortalityHumansMaleMiddle AgedSubarachnoid HemorrhageChinaHospitalization expendituresOut-of-pocketStroke

Identifiers

PMID42163302
PMCPMC13371140

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.