Evidence map›Paper›PMID 42163249›Full record

Trial reportMalaria journal2026

Impact of proactive community case management of malaria on malaria prevalence in Bankass, Mali: a cluster-randomised controlled trial.

Julie Thwing, Saibou Doumbia, Aliou Traore, Mahamadou Sylla, Mahamadou Sogoba, Idrissa Kamara, Yacouba Samaké, Lamine Guindo, Stephanie Rapp, Emily Treleaven and 6 more

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Malaria journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02694055 (Proactive Community Case Management and Child Survival), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02694055 nacompletednot on this map

Proactive Community Case Management and Child Survival: A Cluster-Randomized Controlled Trial

TypeinterventionalSponsorUniversity of California, San FranciscoRan2016 to 2020Enrolled135,149ConditionsUnder-five Child Mortality, Access to Health CareArmsProactive Community Case Management, Integrated Community Case Management, Removal of point-of-care user fees, Infrastructure improvements at primary health centre, Training of primary health centre staff
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Julie ThwingMalaria Branch, Division of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, GA, USA. juliethwing@gmail.com.
Saibou DoumbiaMuso, Bamako, Mali.
Aliou TraoreMalaria Research & Training Centre, Université des Sciences, des Techniques et des Technologies de Bamako, Bamako, Mali.
Mahamadou SyllaNorwegian Refugee Council, Bamako, Mali.
Mahamadou SogobaMuso, Bamako, Mali.
Idrissa KamaraMuso, Bamako, Mali.
Yacouba SamakéCroix Rouge Malienne, Bamako, Mali.
Lamine GuindoMuso, Bamako, Mali.
Stephanie RappMuso, Bamako, Mali.
Emily TreleavenInstitute for Social Research, University of Michigan, Ann Arbor, MI, USA. treleav@umich.edu.
Calvin ChiuInstitute for Health and Aging, University of California, San Francisco, San Francisco, CA, USA.
Caroline WhiddenMuso, Bamako, Mali.
Aminatou KoneMalaria Research & Training Centre, Université des Sciences, des Techniques et des Technologies de Bamako, Bamako, Mali.
Abdoulaye A DjimdeMalaria Research & Training Centre, Université des Sciences, des Techniques et des Technologies de Bamako, Bamako, Mali.
Ari D JohnsonMuso, Bamako, Mali.
Kassoum KayentaoMuso, Bamako, Mali.

Funding

Bill and Melinda Gates Foundation OPP1201366, investment record ID INV-002085Bill & Melinda Gates Foundation INV-002085Grand Challenges Canada 1808-17345, TTS-200237264Johnson & Johnson Foundation 85442, 82844United States Agency for International Development, Development Innovation Lab 7200AA20FA00020
6 · The paper itself

Abstract

backgroundProactive community case management (ProCCM) of malaria is a strategy to improve access to prompt and effective case management of malaria at the community level by supporting community health workers (CHWs) to visit every household in their community every 1 to 2 weeks to identify people with malaria symptoms, offer rapid diagnostic tests, and first line malaria treatment for those with positive tests. We sought to determine if this strategy could decrease malaria parasite prevalence in high malaria transmission settings.

methodsCHWs in the intervention (ProCCM) arm were asked to visit households proactively twice per month to offer an extensive package of maternal and child health services, including malaria case management for males and females of all ages, compared to those in the control arm that offered these services from a fixed point in the community. We measured parasite prevalence among all ages, and fever prevalence, care seeking, and access to diagnostic testing among children under 5 years at the endline survey of a 3-year cluster-randomized controlled trial of ProCCM, covering a population of over 100,000 in Bankass, Mali, a remote rural area that became a conflict zone during the study period.

resultsThere was no difference between intervention and control arms in parasite prevalence among all ages, fever in the last 2 weeks, care seeking, or access to diagnostic testing for malaria among children under 5 years. However, CHWs in the intervention arm reached the goal of two visits per month in less than half the households.

conclusionsIn this high transmission setting, with well-supported, supplied, supervised, and compensated CHWs, both fixed point (control) and proactive household (intervention) visits offered comparable benefits in extending access to malaria case management to community members, despite intervention arm CHWs not reaching the target household visit frequency. Trial registration Trial registration number NCT02694055 (registered February 26, 2016).

Indexed as

Case ManagementCommunity Health WorkersMalariaAdolescentAdultChild, PreschoolFemaleHumansInfantMaleMaliPrevalenceYoung AdultCommunity case managementCommunity health workerHousehold visitMalariaProactive

Identifiers

PMID42163249
PMCPMC13359408

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.