Evidence map›Paper›PMID 42163245›Full record

ArticleBMC health services research2026

Shielding little warriors: enhancing hygiene with chlorhexidine bathing in paediatric oncology - a quality improvement initiative.

Rashmisnata Barman, Amrita Talukdar, L Shangnung, Munlima Hazarika, Bibhuti Bhusan Borthakur, Sarbani Ghosh Laskar

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Article in BMC health services research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Rashmisnata BarmanDepartment of Microbiology, Dr B Borooah Cancer Institute, Room No. 120, OPD Building, Guwahati, Assam, India. drrashmisnata16nabl@gmail.com.
Amrita TalukdarDepartment of Microbiology, Dr B Borooah Cancer Institute, Room No. 120, OPD Building, Guwahati, Assam, India.
L ShangnungInfection Control Nurse (Nurse A), Dr B Borooah Cancer Institute, Guwahati, Assam, India.
Munlima HazarikaDepartment of Medical Oncology, Dr B Borooah Cancer Institute, Guwahati, Assam, India.
Bibhuti Bhusan BorthakurDr B Borooah Cancer Institute, Guwahati, Assam, India.
Sarbani Ghosh LaskarDepartment of Radiation Oncology, Tata Memorial Center, Mumbai, Maharashtra, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPaediatric oncology patients are highly susceptible to healthcare-associated infections (HAIs), particularly central line-associated bloodstream infections (CLABSIs), due to immunosuppression and frequent central venous catheter (CVC) use. Daily bathing with chlorhexidine gluconate (CHG) has demonstrated efficacy in reducing skin colonization by multidrug-resistant organisms (MDROs), yet compliance remains suboptimal in many settings. LOCAL PROBLEM: At our tertiary cancer centre in Northeast India, baseline compliance with daily CHG bathing among paediatric oncology inpatients was 27%, despite institutional guidelines recommending routine use.

methodsA multidisciplinary quality improvement project (QIP) was implemented using A3 methodology. Root cause analysis identified key barriers to compliance. Targeted interventions were deployed over a six-month period from October 2024 to February 2025, supported by EQUIP India under the National Cancer Grid. Compliance was tracked using daily audits and run charts.

resultsInterventions included developing a standard operating procedure (SOP), structured training for staff and caregivers, infrastructure improvements, and enhanced logistical support. Following implementation, mean weekly chlorhexidine gluconate (CHG) bathing compliance improved from a baseline of 27% to 64% by February 2025, exceeding the project target of 60%.

conclusionsA structured, multi-faceted QIP can significantly improve and sustain adherence to CHG bathing protocols in a resource-constrained pediatric oncology setting. Daily chlorhexidine gluconate (CHG) bathing is a low-cost, scalable intervention that enhances infection control. Stakeholder engagement and addressing systemic barriers are critical for success.

Indexed as

Anti-Infective Agents, LocalBathsChlorhexidineCross InfectionQuality ImprovementCatheter-Related InfectionsChildGuideline AdherenceHumansIndiaNeoplasmsAnti-Infective Agents, LocalChlorhexidinechlorhexidine gluconateCentral line-associated bloodstream infectionsChlorhexidine gluconateInfection controlMultidrug-resistant organismsPaediatric oncologyQuality improvement

Identifiers

PMID42163245
PMCPMC13555858

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.