ArticleBMC infectious diseases2026
Whole genome sequencing of SARS-CoV-2: evaluating the genetic diversity of variants circulating in Ebonyi State, Southeastern Nigeria.
Article in BMC infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCOVID-19 is primarily considered a viral respiratory and vascular illness as its causative agent, SARS-CoV-2, predominantly targets the respiratory and vascular systems. Since being declared a global pandemic by the WHO in 2020, SARS-CoV-2 has spread to 223 countries with more than 281 million cases, and an estimated 5.4 million deaths reported globally. The cardinal aim of this study was to assess the genetic diversity of the circulating SARS-CoV-2 in Ebonyi State, Southeastern Nigeria.
methodsOver a span of 24 calendar months (April, 2020 to March, 2022), a total of 20 clinical samples (nasopharyngeal, nasal, and oropharyngeal swabs) from individuals who were previously confirmed to be positive for the SAR-COV-2 virus by real-time polymerase chain reaction (qRT-PCR) were randomly selected and submitted for whole genome sequencing using illumina MiSeq sequencer.
resultsResults indicated a very high predominance of SARS-CoV-2 clade 21D (Eta) and pangolin lineage B.1.525, as 19 out of the 20 sequenced strains belonged to this group, while only one belonged to clade 21B and pangolin lineage B.1.1.318.
conclusionsThis study highlighted the dynamics of the circulating SARS-CoV-2 strains in Nigeria. Information from this study will be very crucial in developing and structuring interventions, adaptation of response strategies, and improved preparedness for potential future public health challenges posed by SARS-CoV-2 strains, with a resultant impact of contributing to the broader global effort in combating the pandemic.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.