ArticleBMC ophthalmology2026
Association between corneal edema and corneal astigmatism after Descemet membrane endothelial keratoplasty.
Article in BMC ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo evaluate changes in corneal astigmatism after DMEK and determine the predictive value of preoperative central corneal thickness (CCT) for postoperative astigmatic change.
methodsFifty-five eyes with Fuchs' endothelial dystrophy (FED) or pseudophakic bullous keratopathy (PBK) undergoing DMEK were analyzed. Auto kerato-refractometer (ARKRT)-derived anterior corneal astigmatic change was defined as the primary outcome in 55 eyes. Anterior-segment optical coherence tomography (AS-OCT)-derived anterior, posterior, and total corneal parameters were analyzed as secondary outcomes in 25 eyes. Vector analysis assessed magnitude and axis changes. Associations between preoperative CCT and postoperative astigmatic change were evaluated; an exploratory ROC analysis was performed for astigmatic change.
resultsMean preoperative CCT was 738.7 ± 99.7 μm, decreasing to 517.5 ± 37.3 μm postoperatively (P < 0.001). Anterior astigmatism measured by ARKRT decreased significantly after DMEK, whereas anterior and total corneal astigmatism measured by AS-OCT showed a similar decreasing trend without statistical significance. Greater preoperative CCT showed a larger postoperative astigmatic change on ARKRT. In ROC analysis based on ARKRT measurements, a preoperative CCT of 790 μm showed modest discrimination for postoperative astigmatic change > 3.0 D (AUC = 0.749; sensitivity 67%, specificity 81%). PBK eyes showed greater anterior flattening and larger reductions in absolute astigmatism than FED eyes.
conclusionsPreoperative corneal edema is associated with postoperative astigmatic change after DMEK. The 790 μm CCT cutoff showed modest discrimination. In eyes with marked edema, staged astigmatic correction may improve refractive outcomes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.